Tags

Type your tag names separated by a space and hit enter

The system of sulfated alpha-(1-->3)-linked D-mannans from the red seaweed Nothogenia fastigiata: structures, antiherpetic and anticoagulant properties.
Carbohydr Res. 1997 Oct 28; 304(1):53-60.CR

Abstract

Structural analysis of two xylomannans extracted from Nothogenia fastigiata was carried out. The results are consistent with the general pattern previously reported for other xylo-mannans of the same system, alpha-(1-->3)-linked D-mannans 2- and 6-sulfated and having single stubs of beta-(1-->2)-linked D-xylose, but one of the new samples contains a significant amount of 2,6-disulfated units. Both xylomannans studied are obtained as complexes with a beta-D-(1-->3)-, alpha-L-(1-->4)-galactan and a beta-D-(1-->3)-, beta-D-(1-->4)-'mixed linkage' xylan co-existing in the seaweed, a fact that limits the accuracy of the data determined. The structures of the galactan and the xylan are similar to those previously informed for this seaweed. The antiviral activity against four different herpes simplex viral strains and the anticoagulant properties of all the xylo-mannans of the system are reported.

Links

Publisher Full Text

Authors+Show Affiliations

Kolender AA
Departamento de Química Orgánica (CIHIDECAR-CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
Pujol CA
No affiliation info available
Damonte EB
No affiliation info available
Matulewicz MC
No affiliation info available
Cerezo AS
No affiliation info available

MeSH

AnticoagulantsAntiviral AgentsCarbohydrate ConformationGalactansGalactoseMagnetic Resonance SpectroscopyMannansMannoseMolecular WeightSeaweedSimplexvirusSulfatesXylansXylose

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9403994

Citation

Kolender, A A., et al. "The System of Sulfated Alpha-(1-->3)-linked D-mannans From the Red Seaweed Nothogenia Fastigiata: Structures, Antiherpetic and Anticoagulant Properties." Carbohydrate Research, vol. 304, no. 1, 1997, pp. 53-60.
Kolender AA, Pujol CA, Damonte EB, et al. The system of sulfated alpha-(1-->3)-linked D-mannans from the red seaweed Nothogenia fastigiata: structures, antiherpetic and anticoagulant properties. Carbohydr Res. 1997;304(1):53-60.
Kolender, A. A., Pujol, C. A., Damonte, E. B., Matulewicz, M. C., & Cerezo, A. S. (1997). The system of sulfated alpha-(1-->3)-linked D-mannans from the red seaweed Nothogenia fastigiata: structures, antiherpetic and anticoagulant properties. Carbohydrate Research, 304(1), 53-60.
Kolender AA, et al. The System of Sulfated Alpha-(1-->3)-linked D-mannans From the Red Seaweed Nothogenia Fastigiata: Structures, Antiherpetic and Anticoagulant Properties. Carbohydr Res. 1997 Oct 28;304(1):53-60. PubMed PMID: 9403994.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The system of sulfated alpha-(1-->3)-linked D-mannans from the red seaweed Nothogenia fastigiata: structures, antiherpetic and anticoagulant properties. AU - Kolender,A A, AU - Pujol,C A, AU - Damonte,E B, AU - Matulewicz,M C, AU - Cerezo,A S, PY - 1997/12/24/pubmed PY - 1997/12/24/medline PY - 1997/12/24/entrez SP - 53 EP - 60 JF - Carbohydrate research JO - Carbohydr Res VL - 304 IS - 1 N2 - Structural analysis of two xylomannans extracted from Nothogenia fastigiata was carried out. The results are consistent with the general pattern previously reported for other xylo-mannans of the same system, alpha-(1-->3)-linked D-mannans 2- and 6-sulfated and having single stubs of beta-(1-->2)-linked D-xylose, but one of the new samples contains a significant amount of 2,6-disulfated units. Both xylomannans studied are obtained as complexes with a beta-D-(1-->3)-, alpha-L-(1-->4)-galactan and a beta-D-(1-->3)-, beta-D-(1-->4)-'mixed linkage' xylan co-existing in the seaweed, a fact that limits the accuracy of the data determined. The structures of the galactan and the xylan are similar to those previously informed for this seaweed. The antiviral activity against four different herpes simplex viral strains and the anticoagulant properties of all the xylo-mannans of the system are reported. SN - 0008-6215 UR - https://www.unboundmedicine.com/medline/citation/9403994/The_system_of_sulfated_alpha__1__>3__linked_D_mannans_from_the_red_seaweed_Nothogenia_fastigiata:_structures_antiherpetic_and_anticoagulant_properties_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0008621597002012 DB - PRIME DP - Unbound Medicine ER -