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An association between subcortical dementia and pernicious anemia--a psychiatric mask.
Compr Psychiatry. 1997 Nov-Dec; 38(6):349-51.CP

Abstract

A case report from our psychiatric ward demonstrates the emergence of two different organic pathologies, a subcortical dementia and a pernicious anemia, preceded by a psychiatric presentation mimicking a dementia of depression. We emphasize that the psychiatric mask and the lack of other clinical and paraclinical cobalamin deficiency signs were the chief obstacles to early diagnosis. Only a complete and thorough assessment allowed the real diagnosis. We describe a subcortical dementia, and after a review of the literature, we support the causalty of B12 hypovitaminosis (pernicious anemia) in the genesis of this dementia, in the absence of other organic causes of mental syndromes and in the presence of a positive and well-maintained response to vitamin B12 administration.

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Authors+Show Affiliations

Saracaceanu E
Department of Psychiatry, Timone Hospital, Marseille, France.
Tramoni AV
No affiliation info available
Henry JM
No affiliation info available

MeSH

AgedAnemia, PerniciousBrainDementiaDepressive Disorder, MajorDiagnosis, DifferentialFemaleHumansInjections, IntramuscularMagnetic Resonance ImagingMental Status ScheduleNeuropsychological TestsVitamin B 12Vitamin B 12 Deficiency

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

9406742

Citation

Saracaceanu, E, et al. "An Association Between Subcortical Dementia and Pernicious Anemia--a Psychiatric Mask." Comprehensive Psychiatry, vol. 38, no. 6, 1997, pp. 349-51.
Saracaceanu E, Tramoni AV, Henry JM. An association between subcortical dementia and pernicious anemia--a psychiatric mask. Compr Psychiatry. 1997;38(6):349-51.
Saracaceanu, E., Tramoni, A. V., & Henry, J. M. (1997). An association between subcortical dementia and pernicious anemia--a psychiatric mask. Comprehensive Psychiatry, 38(6), 349-51.
Saracaceanu E, Tramoni AV, Henry JM. An Association Between Subcortical Dementia and Pernicious Anemia--a Psychiatric Mask. Compr Psychiatry. 1997 Nov-Dec;38(6):349-51. PubMed PMID: 9406742.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An association between subcortical dementia and pernicious anemia--a psychiatric mask. AU - Saracaceanu,E, AU - Tramoni,A V, AU - Henry,J M, PY - 1997/12/24/pubmed PY - 1997/12/24/medline PY - 1997/12/24/entrez SP - 349 EP - 51 JF - Comprehensive psychiatry JO - Compr Psychiatry VL - 38 IS - 6 N2 - A case report from our psychiatric ward demonstrates the emergence of two different organic pathologies, a subcortical dementia and a pernicious anemia, preceded by a psychiatric presentation mimicking a dementia of depression. We emphasize that the psychiatric mask and the lack of other clinical and paraclinical cobalamin deficiency signs were the chief obstacles to early diagnosis. Only a complete and thorough assessment allowed the real diagnosis. We describe a subcortical dementia, and after a review of the literature, we support the causalty of B12 hypovitaminosis (pernicious anemia) in the genesis of this dementia, in the absence of other organic causes of mental syndromes and in the presence of a positive and well-maintained response to vitamin B12 administration. SN - 0010-440X UR - https://www.unboundmedicine.com/medline/citation/9406742/An_association_between_subcortical_dementia_and_pernicious_anemia__a_psychiatric_mask_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0010-440X(97)90932-9 DB - PRIME DP - Unbound Medicine ER -