Tags

Type your tag names separated by a space and hit enter

[The role of extracorporeal membrane oxygenation (ECMO) in current neonatology].
Z Geburtshilfe Neonatol. 1997; 201 Suppl 1:68-76.ZG

Abstract

Two hundred term or near-term neonates were referred to an ECMO center for severe PPHN associated diseases. In 2 time periods from 1987 to 1991 and from 1992 to December 1995 alternative treatment modes were tried in an attempt to obviate ECMO. During the first time period patients underwent a trial of high-frequency oscillatory (HFOV) ventilation before ECMO. In the second time period patients first received inhaled NO followed by HFOV in non-responders. If this also failed HFOV was combined with iNO. In both time periods about 40% of the patients were spared ECMO treatment by these alternative treatment modalities. INO only benefited 15% of the ECMO candidates who apparently had fared just as well on HFOV alone in the preceding time period. While patients who were improved by iNO were spared HFOV with its potential severe complications, i.e. air leaks and cardiocirculatory instability. More extended long-term studies will have to show which of these 2 treatment modalities (iNO or HFOV) should be given-first priority in an attempt to avoid ECMO in neonates with severe respiratory failure.

Authors+Show Affiliations

Kinderklinik Städt, Krankenhaus Heilbronn.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

9410532

Citation

Kachel, W, et al. "[The Role of Extracorporeal Membrane Oxygenation (ECMO) in Current Neonatology]." Zeitschrift Fur Geburtshilfe Und Neonatologie, vol. 201 Suppl 1, 1997, pp. 68-76.
Kachel W, Lasch P, Varnholt V, et al. [The role of extracorporeal membrane oxygenation (ECMO) in current neonatology]. Z Geburtshilfe Neonatol. 1997;201 Suppl 1:68-76.
Kachel, W., Lasch, P., Varnholt, V., Wirth, H., & Quintel, M. (1997). [The role of extracorporeal membrane oxygenation (ECMO) in current neonatology]. Zeitschrift Fur Geburtshilfe Und Neonatologie, 201 Suppl 1, 68-76.
Kachel W, et al. [The Role of Extracorporeal Membrane Oxygenation (ECMO) in Current Neonatology]. Z Geburtshilfe Neonatol. 1997;201 Suppl 1:68-76. PubMed PMID: 9410532.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The role of extracorporeal membrane oxygenation (ECMO) in current neonatology]. AU - Kachel,W, AU - Lasch,P, AU - Varnholt,V, AU - Wirth,H, AU - Quintel,M, PY - 1997/1/1/pubmed PY - 1997/12/31/medline PY - 1997/1/1/entrez SP - 68 EP - 76 JF - Zeitschrift fur Geburtshilfe und Neonatologie JO - Z Geburtshilfe Neonatol VL - 201 Suppl 1 N2 - Two hundred term or near-term neonates were referred to an ECMO center for severe PPHN associated diseases. In 2 time periods from 1987 to 1991 and from 1992 to December 1995 alternative treatment modes were tried in an attempt to obviate ECMO. During the first time period patients underwent a trial of high-frequency oscillatory (HFOV) ventilation before ECMO. In the second time period patients first received inhaled NO followed by HFOV in non-responders. If this also failed HFOV was combined with iNO. In both time periods about 40% of the patients were spared ECMO treatment by these alternative treatment modalities. INO only benefited 15% of the ECMO candidates who apparently had fared just as well on HFOV alone in the preceding time period. While patients who were improved by iNO were spared HFOV with its potential severe complications, i.e. air leaks and cardiocirculatory instability. More extended long-term studies will have to show which of these 2 treatment modalities (iNO or HFOV) should be given-first priority in an attempt to avoid ECMO in neonates with severe respiratory failure. SN - 0948-2393 UR - https://www.unboundmedicine.com/medline/citation/9410532/[The_role_of_extracorporeal_membrane_oxygenation__ECMO__in_current_neonatology]_ L2 - https://medlineplus.gov/pulmonaryhypertension.html DB - PRIME DP - Unbound Medicine ER -