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Mold allergy is a risk factor for persistent cold-like symptoms in children.

Abstract

In winter, children with mold allergy may develop persistent cold-like symptoms (PCLS) that often defy conventional therapy. To investigate the cause of PCLS, we enrolled 44 children (25 with PCLS and 19 controls) in a 2-year study to compare their clinical symptoms and the mold count in their homes. Children with PCLS had a higher percent of eosinophils in nasal smears as compared with those without PCLS (32% vs 26%). On a scale of 0 to 3, the PCLS group had higher symptom scores (P < 0.001 for all symptoms): bloodshot eyes (2.92 vs 0.79), mouth breathing (2.04 vs 0.68), rhinorrhea (2.48 vs 0.89), nasal voice (2.68 vs 1.00), postnasal drip (2.64 vs 0.47), and headache (2.72 vs 0.53) than the non-PCLS group. The clinical scores also correlated significantly with the mold count in the home (the r value ranged from 0.6716 to 0.7450). We conclude that management of children with PCLS should include decreasing humidity and enforcing environmental control to eradicate mold from inside the homes.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Pediatrics, University of Florida College of Medicine, Gainesville 32610, USA.

    Source

    Clinical pediatrics 36:12 1997 Dec pg 695-9

    MeSH

    Adolescent
    Air Microbiology
    Allergens
    Child
    Child, Preschool
    Colony Count, Microbial
    Common Cold
    Conjunctivitis
    Cough
    Eosinophils
    Fungi
    Headache
    Humans
    Humidity
    Mouth Breathing
    Nasal Mucosa
    Regression Analysis
    Rhinitis, Allergic, Perennial
    Risk Factors
    Seasons
    Voice Disorders

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    9415837

    Citation

    Huang, S W., and J W. Kimbrough. "Mold Allergy Is a Risk Factor for Persistent Cold-like Symptoms in Children." Clinical Pediatrics, vol. 36, no. 12, 1997, pp. 695-9.
    Huang SW, Kimbrough JW. Mold allergy is a risk factor for persistent cold-like symptoms in children. Clin Pediatr (Phila). 1997;36(12):695-9.
    Huang, S. W., & Kimbrough, J. W. (1997). Mold allergy is a risk factor for persistent cold-like symptoms in children. Clinical Pediatrics, 36(12), pp. 695-9.
    Huang SW, Kimbrough JW. Mold Allergy Is a Risk Factor for Persistent Cold-like Symptoms in Children. Clin Pediatr (Phila). 1997;36(12):695-9. PubMed PMID: 9415837.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Mold allergy is a risk factor for persistent cold-like symptoms in children. AU - Huang,S W, AU - Kimbrough,J W, PY - 1998/1/7/pubmed PY - 1998/1/7/medline PY - 1998/1/7/entrez SP - 695 EP - 9 JF - Clinical pediatrics JO - Clin Pediatr (Phila) VL - 36 IS - 12 N2 - In winter, children with mold allergy may develop persistent cold-like symptoms (PCLS) that often defy conventional therapy. To investigate the cause of PCLS, we enrolled 44 children (25 with PCLS and 19 controls) in a 2-year study to compare their clinical symptoms and the mold count in their homes. Children with PCLS had a higher percent of eosinophils in nasal smears as compared with those without PCLS (32% vs 26%). On a scale of 0 to 3, the PCLS group had higher symptom scores (P < 0.001 for all symptoms): bloodshot eyes (2.92 vs 0.79), mouth breathing (2.04 vs 0.68), rhinorrhea (2.48 vs 0.89), nasal voice (2.68 vs 1.00), postnasal drip (2.64 vs 0.47), and headache (2.72 vs 0.53) than the non-PCLS group. The clinical scores also correlated significantly with the mold count in the home (the r value ranged from 0.6716 to 0.7450). We conclude that management of children with PCLS should include decreasing humidity and enforcing environmental control to eradicate mold from inside the homes. SN - 0009-9228 UR - https://www.unboundmedicine.com/medline/citation/9415837/Mold_allergy_is_a_risk_factor_for_persistent_cold_like_symptoms_in_children_ L2 - http://journals.sagepub.com/doi/full/10.1177/000992289703601205?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -