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[Clozapine and treatment of negative symptoms].
Encephale 1997; 23 Spec No 4:7-11E

Abstract

The efficacy of conventional neuroleptics in the treatment of the negative symptoms of schizophrenia is highly controversial. Clozapine, the leading atypical neuroleptic, has been shown to be effective, in the majority of the controlled studies, on both the positive and negative symptoms of the disease. It appears to be active vis-à-vis both the primary and secondary negative symptoms. However, several weeks (at least 12) are required for the effect on primary negative symptoms to clearly emerge. The position of clozapine in the treatment of patients presenting with a state of deficiency remains more debatable.

Authors+Show Affiliations

Service Hospitalo-Universitaire de Psychiatrie, CHU Sainte-Marguerite, Marseille.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

9417403

Citation

Lançon, C, et al. "[Clozapine and Treatment of Negative Symptoms]." L'Encephale, vol. 23 Spec No 4, 1997, pp. 7-11.
Lançon C, Farisse J, Llorca PM. [Clozapine and treatment of negative symptoms]. Encephale. 1997;23 Spec No 4:7-11.
Lançon, C., Farisse, J., & Llorca, P. M. (1997). [Clozapine and treatment of negative symptoms]. L'Encephale, 23 Spec No 4, pp. 7-11.
Lançon C, Farisse J, Llorca PM. [Clozapine and Treatment of Negative Symptoms]. Encephale. 1997;23 Spec No 4:7-11. PubMed PMID: 9417403.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clozapine and treatment of negative symptoms]. AU - Lançon,C, AU - Farisse,J, AU - Llorca,P M, PY - 1998/1/7/pubmed PY - 1998/1/7/medline PY - 1998/1/7/entrez SP - 7 EP - 11 JF - L'Encephale JO - Encephale VL - 23 Spec No 4 N2 - The efficacy of conventional neuroleptics in the treatment of the negative symptoms of schizophrenia is highly controversial. Clozapine, the leading atypical neuroleptic, has been shown to be effective, in the majority of the controlled studies, on both the positive and negative symptoms of the disease. It appears to be active vis-à-vis both the primary and secondary negative symptoms. However, several weeks (at least 12) are required for the effect on primary negative symptoms to clearly emerge. The position of clozapine in the treatment of patients presenting with a state of deficiency remains more debatable. SN - 0013-7006 UR - https://www.unboundmedicine.com/medline/citation/9417403/[Clozapine_and_treatment_of_negative_symptoms]_ L2 - https://medlineplus.gov/depression.html DB - PRIME DP - Unbound Medicine ER -