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Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae.
Pediatr Radiol 1998; 28(1):23-9PR

Abstract

Background.

There are few data on clinical, chest radiograph (CXR) or pulmonary function sequelae in children with post-infectious bronchiolitis obliterans (BO) (pulmonary crepitations, abnormalities on CXR, CT, nuclear medicine scans, or bronchography, with a history of past pulmonary infection and in the absence of other underlying pathology).

Objective.

To analyse the methodology of diagnosis, long-term clinical imaging and pulmonary function sequelae of post-infectious BO in children. Materials and methods. Imaging (CXRs, CT and nuclear lung scans) and clinical histories of 19 children were analysed.

Results.

Clinical follow-up (mean 6.8 years), revealed a high incidence of continuing problems (asthma and bronchiectasis). Fixed airway obstruction was the most common pulmonary function sequela. The sequelae on follow-up (mean 5.8 years) CXR were classified into five patterns which are illustrated: unilateral hyperlucency of an enlarged lung/part of lung; complete collapse of the affected lobe; unilateral hyperlucency of a small or normal-sized lung; bilateral hyperlucent lungs and a mixed pattern of persistent collapse, hyperlucency and peribronchial thickening.

Conclusion.

Long-term observations in children with post-infectious BO should be undertaken to detect bronchiectasis and obstructive airway disease. Sequelae evident on CXR, other than those previously described, can be found. Bronchography and/or lung biopsy are not usually required for the diagnosis of post-infectious BO.

Authors+Show Affiliations

Mater Misericordiae Children's Hospital, South Brisbane, Queensland 4101, Australia.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9426269

Citation

Chang, A B., et al. "Post-infectious Bronchiolitis Obliterans: Clinical, Radiological and Pulmonary Function Sequelae." Pediatric Radiology, vol. 28, no. 1, 1998, pp. 23-9.
Chang AB, Masel JP, Masters B. Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae. Pediatr Radiol. 1998;28(1):23-9.
Chang, A. B., Masel, J. P., & Masters, B. (1998). Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae. Pediatric Radiology, 28(1), pp. 23-9.
Chang AB, Masel JP, Masters B. Post-infectious Bronchiolitis Obliterans: Clinical, Radiological and Pulmonary Function Sequelae. Pediatr Radiol. 1998;28(1):23-9. PubMed PMID: 9426269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae. AU - Chang,A B, AU - Masel,J P, AU - Masters,B, PY - 1998/3/28/pubmed PY - 1998/3/28/medline PY - 1998/3/28/entrez SP - 23 EP - 9 JF - Pediatric radiology JO - Pediatr Radiol VL - 28 IS - 1 N2 - Background. There are few data on clinical, chest radiograph (CXR) or pulmonary function sequelae in children with post-infectious bronchiolitis obliterans (BO) (pulmonary crepitations, abnormalities on CXR, CT, nuclear medicine scans, or bronchography, with a history of past pulmonary infection and in the absence of other underlying pathology). Objective. To analyse the methodology of diagnosis, long-term clinical imaging and pulmonary function sequelae of post-infectious BO in children. Materials and methods. Imaging (CXRs, CT and nuclear lung scans) and clinical histories of 19 children were analysed. Results. Clinical follow-up (mean 6.8 years), revealed a high incidence of continuing problems (asthma and bronchiectasis). Fixed airway obstruction was the most common pulmonary function sequela. The sequelae on follow-up (mean 5.8 years) CXR were classified into five patterns which are illustrated: unilateral hyperlucency of an enlarged lung/part of lung; complete collapse of the affected lobe; unilateral hyperlucency of a small or normal-sized lung; bilateral hyperlucent lungs and a mixed pattern of persistent collapse, hyperlucency and peribronchial thickening. Conclusion. Long-term observations in children with post-infectious BO should be undertaken to detect bronchiectasis and obstructive airway disease. Sequelae evident on CXR, other than those previously described, can be found. Bronchography and/or lung biopsy are not usually required for the diagnosis of post-infectious BO. SN - 0301-0449 UR - https://www.unboundmedicine.com/medline/citation/9426269/Post_infectious_bronchiolitis_obliterans:_clinical_radiological_and_pulmonary_function_sequelae_ L2 - https://dx.doi.org/10.1007/s002470050286 DB - PRIME DP - Unbound Medicine ER -