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Dementia with Lewy bodies.
Baillieres Clin Neurol. 1997 Apr; 6(1):147-66.BC

Abstract

Dementia with Lewy bodies (DLB) is the recommended term for a common cause of dementia characterized by the histological presence of distinctive inclusions within neurons, Lewy bodies (McKeith et al, 1996). Following increasing pathological recognition, core clinical diagnostic features have been identified to allow diagnosis in life. Insights into the biology of this type of neurodegeneration suggest that the regional patterns of involvement might allow therapeutic intervention. Although Lewy bodies had long been recognized in the substantia nigra and other subcortical nuclei in patients with Parkinson's disease (PD), it was only in the 1970s that a significant number of reports began to be published from Japan describing patients with dementia and parkinsonism associated with the presence of Lewy bodies in cortical neurons (reviewed by Kosaka, 1990). Since these reports, different workers have used a variety of terms to describe this disease process, including diffuse Lewy body disease (Yoshimura, 1983), Lewy body dementia (Gibb et al, 1987), senile dementia of Lewy body type (Perry et al, 1990a) and the Lewy body variant of Alzheimer's disease (Hansen et al, 1990).

Authors+Show Affiliations

University of Nottingham, UK.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9426873

Citation

Lennox, G G., and J S. Lowe. "Dementia With Lewy Bodies." Bailliere's Clinical Neurology, vol. 6, no. 1, 1997, pp. 147-66.
Lennox GG, Lowe JS. Dementia with Lewy bodies. Baillieres Clin Neurol. 1997;6(1):147-66.
Lennox, G. G., & Lowe, J. S. (1997). Dementia with Lewy bodies. Bailliere's Clinical Neurology, 6(1), 147-66.
Lennox GG, Lowe JS. Dementia With Lewy Bodies. Baillieres Clin Neurol. 1997;6(1):147-66. PubMed PMID: 9426873.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dementia with Lewy bodies. AU - Lennox,G G, AU - Lowe,J S, PY - 1997/4/1/pubmed PY - 1998/1/14/medline PY - 1997/4/1/entrez SP - 147 EP - 66 JF - Bailliere's clinical neurology JO - Baillieres Clin Neurol VL - 6 IS - 1 N2 - Dementia with Lewy bodies (DLB) is the recommended term for a common cause of dementia characterized by the histological presence of distinctive inclusions within neurons, Lewy bodies (McKeith et al, 1996). Following increasing pathological recognition, core clinical diagnostic features have been identified to allow diagnosis in life. Insights into the biology of this type of neurodegeneration suggest that the regional patterns of involvement might allow therapeutic intervention. Although Lewy bodies had long been recognized in the substantia nigra and other subcortical nuclei in patients with Parkinson's disease (PD), it was only in the 1970s that a significant number of reports began to be published from Japan describing patients with dementia and parkinsonism associated with the presence of Lewy bodies in cortical neurons (reviewed by Kosaka, 1990). Since these reports, different workers have used a variety of terms to describe this disease process, including diffuse Lewy body disease (Yoshimura, 1983), Lewy body dementia (Gibb et al, 1987), senile dementia of Lewy body type (Perry et al, 1990a) and the Lewy body variant of Alzheimer's disease (Hansen et al, 1990). SN - 0961-0421 UR - https://www.unboundmedicine.com/medline/citation/9426873/Dementia_with_Lewy_bodies_ L2 - https://medlineplus.gov/dementia.html DB - PRIME DP - Unbound Medicine ER -