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[The effectiveness of amantadine (midantan) in the treatment of the parkinsonian syndrome].

Abstract

The author treated 83 patients with parkinsonism by analouges of amantadin--the Soviet preparation midantan and Swiss preparation simmetril. Twenty patients received only Amantadin and 63 Amantadin in combination with other antiparkinsonic drugs. Optimal doses of other antiparkinsonic drugs were determined prior to amantadin treatment. The preparation exerted a higher influence on such symptoms of parkinsonism as akinesis and rigidity and less on tremor. In 1/3 of the cases a positive effect of the treatment was temporary and disappeared altogether after 2--4 weeks despite the continuation of therapy. The preparation was well tolerated. Side effects observed in 32 of the 83 patients were usually expressed very midly and disappeared without special treatment. The author compares such preparations al 1-Dopa and Amantadin (Midantan).

Authors

No affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

944514

Citation

Kadykov, A S.. "[The Effectiveness of Amantadine (midantan) in the Treatment of the Parkinsonian Syndrome]." Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), vol. 76, no. 2, 1976, pp. 174-8.
Kadykov AS. [The effectiveness of amantadine (midantan) in the treatment of the parkinsonian syndrome]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(2):174-8.
Kadykov, A. S. (1976). [The effectiveness of amantadine (midantan) in the treatment of the parkinsonian syndrome]. Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), 76(2), 174-8.
Kadykov AS. [The Effectiveness of Amantadine (midantan) in the Treatment of the Parkinsonian Syndrome]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(2):174-8. PubMed PMID: 944514.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The effectiveness of amantadine (midantan) in the treatment of the parkinsonian syndrome]. A1 - Kadykov,A S, PY - 1976/1/1/pubmed PY - 1976/1/1/medline PY - 1976/1/1/entrez SP - 174 EP - 8 JF - Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) JO - Zh Nevropatol Psikhiatr Im S S Korsakova VL - 76 IS - 2 N2 - The author treated 83 patients with parkinsonism by analouges of amantadin--the Soviet preparation midantan and Swiss preparation simmetril. Twenty patients received only Amantadin and 63 Amantadin in combination with other antiparkinsonic drugs. Optimal doses of other antiparkinsonic drugs were determined prior to amantadin treatment. The preparation exerted a higher influence on such symptoms of parkinsonism as akinesis and rigidity and less on tremor. In 1/3 of the cases a positive effect of the treatment was temporary and disappeared altogether after 2--4 weeks despite the continuation of therapy. The preparation was well tolerated. Side effects observed in 32 of the 83 patients were usually expressed very midly and disappeared without special treatment. The author compares such preparations al 1-Dopa and Amantadin (Midantan). SN - 0044-4588 UR - https://www.unboundmedicine.com/medline/citation/944514/[The_effectiveness_of_amantadine__midantan__in_the_treatment_of_the_parkinsonian_syndrome]_ DB - PRIME DP - Unbound Medicine ER -