TY - JOUR T1 - Effects of supplemental vitamin E and canola oil on tissue tocopherol and liver fatty acid profile of finishing swine. AU - Soler-Velasquez,M P, AU - Brendemuhl,J H, AU - McDowell,L R, AU - Sheppard,K A, AU - Johnson,D D, AU - Williams,S N, PY - 1998/2/17/pubmed PY - 1998/2/17/medline PY - 1998/2/17/entrez SP - 110 EP - 7 JF - Journal of animal science JO - J Anim Sci VL - 76 IS - 1 N2 - We conducted a 4 x 3 factorial experiment with finishing pigs for 6 wk to evaluate effects of dietary canola oil and vitamin E on vitamin E status and liver fatty acid profile. Treatments consisted of four supplemental levels of vitamin E (0, 50, 125, and 200 mg/kg) and three of canola oil (0, 5, and 10% of the diet). Serum was collected each week and tissue samples at d 42. Dietary canola oil (P = .02) and vitamin E (P < .001) increased serum alpha-tocopherol. Serum alpha-tocopherol reached a plateau at d 35 of vitamin E and canola oil supplementation. An interaction was observed between canola oil and vitamin E (P = .02) for liver alpha-tocopherol. Liver alpha-tocopherol was greater in pigs fed diets with 10% canola oil and supplemented with 125 or 200 mg/kg of vitamin E than in pigs fed diets with 0 and 5% canola oil. An interaction also occurred between canola oil and vitamin E (P = .01) for alpha-tocopherol in the gluteus medius and obliquus capitis caudalis muscles. A greater magnitude of increase in muscle alpha-tocopherol was observed in pigs fed diets with no canola oil than in pigs fed diets with 5 and 10% canola oil. Highest alpha-tocopherol was in liver, followed by obliquus capitis caudalis and then gluteus medius. Inclusion of 5 or 10% dietary canola oil decreased the amount of saturated fatty acids by 4.1 and 13.5%, increased monounsaturated fatty acids by 10.9 and 39.3%, respectively, and had no effect (P > .10) on total polyunsaturated fatty acids. Canola oil increased linoleic acid [18:2(n-6)] (quadratic, P = .05) and linolenic acid [18:3(n-3)] (linear, P < .001) while decreasing arachidonic acid [20:4(n-6)] and docosadienoic acid (20:2) linearly (P < .001 and P = .02, respectively). Dietary canola oil and vitamin E increased serum and tissue alpha-tocopherol; canola oil increased monounsaturated and decreased saturated fatty acids in liver. SN - 0021-8812 UR - https://www.unboundmedicine.com/medline/citation/9464891/Effects_of_supplemental_vitamin_E_and_canola_oil_on_tissue_tocopherol_and_liver_fatty_acid_profile_of_finishing_swine_ L2 - https://academic.oup.com/jas/article-lookup/doi/10.2527/1998.761110x DB - PRIME DP - Unbound Medicine ER -