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Measuring duodenogastro-oesophageal reflux (DGOR)
Eur J Gastroenterol Hepatol 1997; 9(12):1141-3EJ

Abstract

The importance of duodenogastro-oesophageal reflux (DGOR) in gastro-oesophageal reflux disease (GORD) is controversial. Most evidence points to a possible synergistic effect between refluxed acid and bile, which may be more frequent in patients with Barrett's oesophagus, particularly those with complications. Techniques for long-term measurement of DGOR include continuous aspiration, which is cumbersome and laborious, ambulatory spectrophotometric bilirubin measurement as a proxy for bile acids and sodium ion measurement using a sodium electrode. The two latter are the most promising techniques which are improving understanding of DGOR in clinical situations. Both have advantages and drawbacks. The Bilitec system for measuring bilirubin has been most studied and has been well validated. The sodium electrode has so far only been used for short-term monitoring but may be capable of development into a practical tool for longer-term monitoring of DGOR.

Authors+Show Affiliations

Department of Medicine, Glenfield Hospital, Leicester, UK.

Pub Type(s)

Comment
Journal Article

Language

eng

PubMed ID

9471017

Citation

de Caestecker, J S.. "Measuring Duodenogastro-oesophageal Reflux (DGOR)." European Journal of Gastroenterology & Hepatology, vol. 9, no. 12, 1997, pp. 1141-3.
de Caestecker JS. Measuring duodenogastro-oesophageal reflux (DGOR). Eur J Gastroenterol Hepatol. 1997;9(12):1141-3.
de Caestecker, J. S. (1997). Measuring duodenogastro-oesophageal reflux (DGOR). European Journal of Gastroenterology & Hepatology, 9(12), pp. 1141-3.
de Caestecker JS. Measuring Duodenogastro-oesophageal Reflux (DGOR). Eur J Gastroenterol Hepatol. 1997;9(12):1141-3. PubMed PMID: 9471017.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Measuring duodenogastro-oesophageal reflux (DGOR) A1 - de Caestecker,J S, PY - 1998/2/21/pubmed PY - 1998/2/21/medline PY - 1998/2/21/entrez SP - 1141 EP - 3 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 9 IS - 12 N2 - The importance of duodenogastro-oesophageal reflux (DGOR) in gastro-oesophageal reflux disease (GORD) is controversial. Most evidence points to a possible synergistic effect between refluxed acid and bile, which may be more frequent in patients with Barrett's oesophagus, particularly those with complications. Techniques for long-term measurement of DGOR include continuous aspiration, which is cumbersome and laborious, ambulatory spectrophotometric bilirubin measurement as a proxy for bile acids and sodium ion measurement using a sodium electrode. The two latter are the most promising techniques which are improving understanding of DGOR in clinical situations. Both have advantages and drawbacks. The Bilitec system for measuring bilirubin has been most studied and has been well validated. The sodium electrode has so far only been used for short-term monitoring but may be capable of development into a practical tool for longer-term monitoring of DGOR. SN - 0954-691X UR - https://www.unboundmedicine.com/medline/citation/9471017/Measuring_duodenogastro_oesophageal_reflux__DGOR_ L2 - https://medlineplus.gov/gerd.html DB - PRIME DP - Unbound Medicine ER -