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[Endocrine tumors of the pancreas].
Rev Gastroenterol Mex. 1997 Jul-Sep; 62(3):212-7.RG

Abstract

BACKGROUND

Endocrine tumors of the pancreas arise from pancreatic and duodenal neuroendocrine cells.

OBJECTIVE

To review clinical features, diagnosis and treatment of endocrine tumors of pancreas, as well as our experience at the Instituto Nacional de la Nutrición "Salvador Zubirán" (INNSZ).

RESULTS

Endocrine tumors of pancreas are slow growing tumors. The most frequent tumors are insulinoma, gastrinoma and non-functioning tumors. Clinical picture of functioning tumors is determined by the action of the secreting hormone, and the diagnosis is established once high levels of the tumor secretin peptide are demonstrated. In order to localize the tumor and to search for metastasis, several imaging studies have been used. In general, image studies have demonstrated poor sensitivity in finding the primary lesion. Recently, dynamic studies have shown their ability to regionalize the peptide increase. Endoscopic and intraoperative ultrasound have shown promising results. Surgical resection is the only curative treatment, resection of hepatic metastasis can even improve survival. In the INNSZ, 38 patients with endocrine tumors of the pancreas have received initial treatment in a 32-year period. The most common neoplasia is the insulinoma, followed by non-functioning tumors and gastrinoma. Most insulinomas were benign, where as the malignancy rate of non-functioning.

CONCLUSIONS

Endocrine tumors of the pancreas are rare lesions, with a variety of clinical pictures related to the hormone produced. Localizing studies are generally poor. Favorable outcome meaning cure of benign lesions or long survival despite the presence of malignancy occur in most patients.

Authors+Show Affiliations

Departamento de Cirugía, Instituto Nacional de la Nutrición Salvador Zubirán, México, D. F., México.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

spa

PubMed ID

9480529

Citation

Lozano-Salazar, R R., et al. "[Endocrine Tumors of the Pancreas]." Revista De Gastroenterologia De Mexico, vol. 62, no. 3, 1997, pp. 212-7.
Lozano-Salazar RR, Herrera MF, Hernández-Ortiz J, et al. [Endocrine tumors of the pancreas]. Rev Gastroenterol Mex. 1997;62(3):212-7.
Lozano-Salazar, R. R., Herrera, M. F., Hernández-Ortiz, J., & Campuzano, M. (1997). [Endocrine tumors of the pancreas]. Revista De Gastroenterologia De Mexico, 62(3), 212-7.
Lozano-Salazar RR, et al. [Endocrine Tumors of the Pancreas]. Rev Gastroenterol Mex. 1997 Jul-Sep;62(3):212-7. PubMed PMID: 9480529.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Endocrine tumors of the pancreas]. AU - Lozano-Salazar,R R, AU - Herrera,M F, AU - Hernández-Ortiz,J, AU - Campuzano,M, PY - 1997/7/1/pubmed PY - 1998/2/28/medline PY - 1997/7/1/entrez SP - 212 EP - 7 JF - Revista de gastroenterologia de Mexico JO - Rev Gastroenterol Mex VL - 62 IS - 3 N2 - BACKGROUND: Endocrine tumors of the pancreas arise from pancreatic and duodenal neuroendocrine cells. OBJECTIVE: To review clinical features, diagnosis and treatment of endocrine tumors of pancreas, as well as our experience at the Instituto Nacional de la Nutrición "Salvador Zubirán" (INNSZ). RESULTS: Endocrine tumors of pancreas are slow growing tumors. The most frequent tumors are insulinoma, gastrinoma and non-functioning tumors. Clinical picture of functioning tumors is determined by the action of the secreting hormone, and the diagnosis is established once high levels of the tumor secretin peptide are demonstrated. In order to localize the tumor and to search for metastasis, several imaging studies have been used. In general, image studies have demonstrated poor sensitivity in finding the primary lesion. Recently, dynamic studies have shown their ability to regionalize the peptide increase. Endoscopic and intraoperative ultrasound have shown promising results. Surgical resection is the only curative treatment, resection of hepatic metastasis can even improve survival. In the INNSZ, 38 patients with endocrine tumors of the pancreas have received initial treatment in a 32-year period. The most common neoplasia is the insulinoma, followed by non-functioning tumors and gastrinoma. Most insulinomas were benign, where as the malignancy rate of non-functioning. CONCLUSIONS: Endocrine tumors of the pancreas are rare lesions, with a variety of clinical pictures related to the hormone produced. Localizing studies are generally poor. Favorable outcome meaning cure of benign lesions or long survival despite the presence of malignancy occur in most patients. SN - 0375-0906 UR - https://www.unboundmedicine.com/medline/citation/9480529/[Endocrine_tumors_of_the_pancreas]_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -