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[Candida albicans sensitization in patients with atopic bronchial asthma and atopic dermatitis].
Ter Arkh. 1997; 69(11):41-4.TA

Abstract

Candida albicans, a component of normal human microflora, can induce synthesis of specific IgE-antibodies in patients with atopic bronchial asthma and atopic dermatitis. The study included 25 patients with atopic dermatitis sensitized to C.albicans and 23 patients with atopic dermatitis non-sensitized to C.albicans. The sensitization was determined by the skin test and enzyme immunoassay. The patients had the history of atopic dermatitis exacerbation after taking food containing baking yeasts. Atopic dermatitis with sensitization to C.albicans is characterized by severe course correlating with the following indices: high total IgE (r = 0.6), level of IgE antibodies to C.albicans (r = 0.6), level of serum IgG (r = 0.46) and IgA (r = 0.33). Contrary to adults, children with sensitization to C.albicans had decreased relative number of CD4+, CD8+ and CD72+ of lymphocyte subpopulations. Thus, sensitization to C.albicans manifests in severe atopic dermatitis which in children is often associated with immune deficiency.

Authors

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Pub Type(s)

Comparative Study
Journal Article

Language

rus

PubMed ID

9483746

Citation

Samuĭlova, T L., et al. "[Candida Albicans Sensitization in Patients With Atopic Bronchial Asthma and Atopic Dermatitis]." Terapevticheskii Arkhiv, vol. 69, no. 11, 1997, pp. 41-4.
Samuĭlova TL, Mokronosova MA, Krasnoproshina LI, et al. [Candida albicans sensitization in patients with atopic bronchial asthma and atopic dermatitis]. Ter Arkh. 1997;69(11):41-4.
Samuĭlova, T. L., Mokronosova, M. A., Krasnoproshina, L. I., Sdokhova, S. A., & Sergeeva, A. S. (1997). [Candida albicans sensitization in patients with atopic bronchial asthma and atopic dermatitis]. Terapevticheskii Arkhiv, 69(11), 41-4.
Samuĭlova TL, et al. [Candida Albicans Sensitization in Patients With Atopic Bronchial Asthma and Atopic Dermatitis]. Ter Arkh. 1997;69(11):41-4. PubMed PMID: 9483746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Candida albicans sensitization in patients with atopic bronchial asthma and atopic dermatitis]. AU - Samuĭlova,T L, AU - Mokronosova,M A, AU - Krasnoproshina,L I, AU - Sdokhova,S A, AU - Sergeeva,A S, PY - 1997/1/1/pubmed PY - 1998/3/4/medline PY - 1997/1/1/entrez SP - 41 EP - 4 JF - Terapevticheskii arkhiv JO - Ter Arkh VL - 69 IS - 11 N2 - Candida albicans, a component of normal human microflora, can induce synthesis of specific IgE-antibodies in patients with atopic bronchial asthma and atopic dermatitis. The study included 25 patients with atopic dermatitis sensitized to C.albicans and 23 patients with atopic dermatitis non-sensitized to C.albicans. The sensitization was determined by the skin test and enzyme immunoassay. The patients had the history of atopic dermatitis exacerbation after taking food containing baking yeasts. Atopic dermatitis with sensitization to C.albicans is characterized by severe course correlating with the following indices: high total IgE (r = 0.6), level of IgE antibodies to C.albicans (r = 0.6), level of serum IgG (r = 0.46) and IgA (r = 0.33). Contrary to adults, children with sensitization to C.albicans had decreased relative number of CD4+, CD8+ and CD72+ of lymphocyte subpopulations. Thus, sensitization to C.albicans manifests in severe atopic dermatitis which in children is often associated with immune deficiency. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/9483746/[Candida_albicans_sensitization_in_patients_with_atopic_bronchial_asthma_and_atopic_dermatitis]_ L2 - http://www.diseaseinfosearch.org/result/633 DB - PRIME DP - Unbound Medicine ER -