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Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors.
Cancer Epidemiol Biomarkers Prev. 1998 Mar; 7(3):231-5.CE

Abstract

A large case-control study was performed to determine whether risk factors for endometrioid carcinoma, the most common type of endometrial cancer, vary according to the histological features of the tumor. Study subjects consisted of 328 women with newly diagnosed endometrioid adenocarcinoma and 320 population-based control subjects. Variables studied included age at menarche, menopausal estrogen use, weight, parity, cigarette smoking, and oral contraceptive use. The risk factor profile for endometrioid carcinomas with and without squamous differentiation was very similar. No striking differences in risk factors were observed between endometrioid cancers with and without adjacent endometrial hyperplasia. Finally, none of the risk factors varied substantially between early-stage and late-stage tumors or low-grade and high-grade tumors. In summary, this study indicates that risk factors for endometrioid carcinomas are not related to the morphological features of the tumor.

Authors+Show Affiliations

Environmental Epidemiology Branch, National Cancer Institute, Rockville, Maryland 20852, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9521439

Citation

Sturgeon, S R., et al. "Analysis of Histopathological Features of Endometrioid Uterine Carcinomas and Epidemiologic Risk Factors." Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology, vol. 7, no. 3, 1998, pp. 231-5.
Sturgeon SR, Sherman ME, Kurman RJ, et al. Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. Cancer Epidemiol Biomarkers Prev. 1998;7(3):231-5.
Sturgeon, S. R., Sherman, M. E., Kurman, R. J., Berman, M. L., Mortel, R., Twiggs, L. B., Barrett, R. J., Wilbanks, G. D., & Brinton, L. A. (1998). Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology, 7(3), 231-5.
Sturgeon SR, et al. Analysis of Histopathological Features of Endometrioid Uterine Carcinomas and Epidemiologic Risk Factors. Cancer Epidemiol Biomarkers Prev. 1998;7(3):231-5. PubMed PMID: 9521439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. AU - Sturgeon,S R, AU - Sherman,M E, AU - Kurman,R J, AU - Berman,M L, AU - Mortel,R, AU - Twiggs,L B, AU - Barrett,R J, AU - Wilbanks,G D, AU - Brinton,L A, PY - 1998/4/1/pubmed PY - 1998/4/1/medline PY - 1998/4/1/entrez SP - 231 EP - 5 JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology JO - Cancer Epidemiol. Biomarkers Prev. VL - 7 IS - 3 N2 - A large case-control study was performed to determine whether risk factors for endometrioid carcinoma, the most common type of endometrial cancer, vary according to the histological features of the tumor. Study subjects consisted of 328 women with newly diagnosed endometrioid adenocarcinoma and 320 population-based control subjects. Variables studied included age at menarche, menopausal estrogen use, weight, parity, cigarette smoking, and oral contraceptive use. The risk factor profile for endometrioid carcinomas with and without squamous differentiation was very similar. No striking differences in risk factors were observed between endometrioid cancers with and without adjacent endometrial hyperplasia. Finally, none of the risk factors varied substantially between early-stage and late-stage tumors or low-grade and high-grade tumors. In summary, this study indicates that risk factors for endometrioid carcinomas are not related to the morphological features of the tumor. SN - 1055-9965 UR - https://www.unboundmedicine.com/medline/citation/9521439/Analysis_of_histopathological_features_of_endometrioid_uterine_carcinomas_and_epidemiologic_risk_factors_ L2 - http://cebp.aacrjournals.org/cgi/pmidlookup?view=long&pmid=9521439 DB - PRIME DP - Unbound Medicine ER -