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[Production of fungal antigens from local strains for the immunodiagnosis of mycoses in Mexico].
Rev Invest Clin. 1997 Nov-Dec; 49(6):501-5.RI

Abstract

Fungal antigens with good reactivity and specificity are essential for the immunodiagnosis of systemic mycoses. We give here data on crude and purified antigens of Histoplasma capsulatum, Coccidioidis immitis and Paracoccidioides brasiliensis from local strains and which are the more prevalent in Mexico. The crude antigens had good reactivity in precipitating and skin testing whereas the purified antigens (DPPC: deproteinized polysaccharide protein complex) had a higher specificity in more sensitive tests such as ELISA and complement fixation. Our efficiency analysis showed that the crude antigens are best for epidemiologic studies due to their low cost, easy handling and fast detection. The purified ones are suited to establish with more precision the diagnosis of systemic mycoses.

Authors+Show Affiliations

Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, México, D.F. toriello@servidor.unam.mxNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

spa

PubMed ID

9528311

Citation

Toriello, C, et al. "[Production of Fungal Antigens From Local Strains for the Immunodiagnosis of Mycoses in Mexico]." Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, vol. 49, no. 6, 1997, pp. 501-5.
Toriello C, Reyes-Montes MR, Taylor ML. [Production of fungal antigens from local strains for the immunodiagnosis of mycoses in Mexico]. Rev Invest Clin. 1997;49(6):501-5.
Toriello, C., Reyes-Montes, M. R., & Taylor, M. L. (1997). [Production of fungal antigens from local strains for the immunodiagnosis of mycoses in Mexico]. Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, 49(6), 501-5.
Toriello C, Reyes-Montes MR, Taylor ML. [Production of Fungal Antigens From Local Strains for the Immunodiagnosis of Mycoses in Mexico]. Rev Invest Clin. 1997 Nov-Dec;49(6):501-5. PubMed PMID: 9528311.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Production of fungal antigens from local strains for the immunodiagnosis of mycoses in Mexico]. AU - Toriello,C, AU - Reyes-Montes,M R, AU - Taylor,M L, PY - 1998/4/7/pubmed PY - 1998/4/7/medline PY - 1998/4/7/entrez SP - 501 EP - 5 JF - Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion JO - Rev Invest Clin VL - 49 IS - 6 N2 - Fungal antigens with good reactivity and specificity are essential for the immunodiagnosis of systemic mycoses. We give here data on crude and purified antigens of Histoplasma capsulatum, Coccidioidis immitis and Paracoccidioides brasiliensis from local strains and which are the more prevalent in Mexico. The crude antigens had good reactivity in precipitating and skin testing whereas the purified antigens (DPPC: deproteinized polysaccharide protein complex) had a higher specificity in more sensitive tests such as ELISA and complement fixation. Our efficiency analysis showed that the crude antigens are best for epidemiologic studies due to their low cost, easy handling and fast detection. The purified ones are suited to establish with more precision the diagnosis of systemic mycoses. SN - 0034-8376 UR - https://www.unboundmedicine.com/medline/citation/9528311/[Production_of_fungal_antigens_from_local_strains_for_the_immunodiagnosis_of_mycoses_in_Mexico]_ L2 - https://medlineplus.gov/fungalinfections.html DB - PRIME DP - Unbound Medicine ER -