Tags

Type your tag names separated by a space and hit enter

Vitamin D deficiency in pregnancy is not associated with obstructed labor. A study among Pakistani women in Karachi.
Acta Obstet Gynecol Scand. 1998 Mar; 77(3):303-6.AO

Abstract

BACKGROUND

Vitamin D deficiency is widespread among pregnant Pakistanis in Norway. It may cause osteomalacia with destruction of maternal pelvis, and thus be a risk factor for cephalopelvic disproportion. This study was performed to determine whether vitamin D deficiency is common among pregnant Pakistanis in Pakistan, and to test the hypothesis that vitamin D deficiency in nulliparous pregnant women is associated with mechanical dystocia.

METHODS

The study was carried out at the Civil Hospital, in a poor area of Karachi, and had a case-referent design. Thirty-seven nulliparous parturients with Cesarean section due to mechanical dystocia served as cases, and 80 nulliparous parturients with uncomplicated vaginal delivery were their referents. All blood samples were drawn before parturition.

RESULTS

The mothers with obstructed labor were shorter (on average 150 vs. 155 cm, p= 0.0001) and lighter (on average 58 vs. 60.5 kg, p=0.005) than their referents. Seventy-one percent (83/117) of all the participants had marginal or low vitamin D status defined as serum level of calcidiol (25-OH vitamin D3) below 30 nmol/l. Vitamin D deficiency was, however, not more widespread among the mothers with obstructed labor (20/37 vs. 63/80). Furthermore, there were no significant differences in the serum levels of the carboxyterminal telopeptide of type I collagen, a sensitive biochemical marker of bone resorption, (7.2 vs. 6.6 microg/l), and bone specific alkaline phosphate (18.1 vs. 22.0 U/l) a sensitive marker of bone formation.

CONCLUSIONS

Vitamin D deficiency in pregnancy is common in Karachi, but is not associated with mechanical dystocia.

Authors+Show Affiliations

Department of Pediatrics, Ullevål Hospital, Oslo, Norway.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

9539276

Citation

Brunvand, L, et al. "Vitamin D Deficiency in Pregnancy Is Not Associated With Obstructed Labor. a Study Among Pakistani Women in Karachi." Acta Obstetricia Et Gynecologica Scandinavica, vol. 77, no. 3, 1998, pp. 303-6.
Brunvand L, Shah SS, Bergström S, et al. Vitamin D deficiency in pregnancy is not associated with obstructed labor. A study among Pakistani women in Karachi. Acta Obstet Gynecol Scand. 1998;77(3):303-6.
Brunvand, L., Shah, S. S., Bergström, S., & Haug, E. (1998). Vitamin D deficiency in pregnancy is not associated with obstructed labor. A study among Pakistani women in Karachi. Acta Obstetricia Et Gynecologica Scandinavica, 77(3), 303-6.
Brunvand L, et al. Vitamin D Deficiency in Pregnancy Is Not Associated With Obstructed Labor. a Study Among Pakistani Women in Karachi. Acta Obstet Gynecol Scand. 1998;77(3):303-6. PubMed PMID: 9539276.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin D deficiency in pregnancy is not associated with obstructed labor. A study among Pakistani women in Karachi. AU - Brunvand,L, AU - Shah,S S, AU - Bergström,S, AU - Haug,E, PY - 1998/4/16/pubmed PY - 1998/4/16/medline PY - 1998/4/16/entrez KW - Asia KW - Biology KW - Body Height KW - Case Control Studies KW - Deficiency Diseases KW - Delivery KW - Developing Countries KW - Diseases KW - Nutrition Disorders KW - Pakistan KW - Physiology KW - Pregnancy KW - Pregnancy Complications KW - Pregnancy Outcomes KW - Reproduction KW - Research Methodology KW - Research Report KW - Risk Factors KW - Southern Asia KW - Studies KW - Vitamins SP - 303 EP - 6 JF - Acta obstetricia et gynecologica Scandinavica JO - Acta Obstet Gynecol Scand VL - 77 IS - 3 N2 - BACKGROUND: Vitamin D deficiency is widespread among pregnant Pakistanis in Norway. It may cause osteomalacia with destruction of maternal pelvis, and thus be a risk factor for cephalopelvic disproportion. This study was performed to determine whether vitamin D deficiency is common among pregnant Pakistanis in Pakistan, and to test the hypothesis that vitamin D deficiency in nulliparous pregnant women is associated with mechanical dystocia. METHODS: The study was carried out at the Civil Hospital, in a poor area of Karachi, and had a case-referent design. Thirty-seven nulliparous parturients with Cesarean section due to mechanical dystocia served as cases, and 80 nulliparous parturients with uncomplicated vaginal delivery were their referents. All blood samples were drawn before parturition. RESULTS: The mothers with obstructed labor were shorter (on average 150 vs. 155 cm, p= 0.0001) and lighter (on average 58 vs. 60.5 kg, p=0.005) than their referents. Seventy-one percent (83/117) of all the participants had marginal or low vitamin D status defined as serum level of calcidiol (25-OH vitamin D3) below 30 nmol/l. Vitamin D deficiency was, however, not more widespread among the mothers with obstructed labor (20/37 vs. 63/80). Furthermore, there were no significant differences in the serum levels of the carboxyterminal telopeptide of type I collagen, a sensitive biochemical marker of bone resorption, (7.2 vs. 6.6 microg/l), and bone specific alkaline phosphate (18.1 vs. 22.0 U/l) a sensitive marker of bone formation. CONCLUSIONS: Vitamin D deficiency in pregnancy is common in Karachi, but is not associated with mechanical dystocia. SN - 0001-6349 UR - https://www.unboundmedicine.com/medline/citation/9539276/Vitamin_D_deficiency_in_pregnancy_is_not_associated_with_obstructed_labor__A_study_among_Pakistani_women_in_Karachi_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=9539276.ui DB - PRIME DP - Unbound Medicine ER -