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The free radicals--the hidden culprits--an update.
Indian J Med Sci 1997; 51(9):319-36IJ

Abstract

Free radicals are normally produced as a by-product of cellular metabolism. Free radicals are capable of killing bacteria, damage biomolecules, provoke immune response, activate oncogens, cause atherogenesis and enhance ageing process. However, in healthy conditions nature has endowed human body with enormous antioxidant potential. Subtle balance exists between free radical generation and antioxidant defence system to cope with oxidative stress by various enzymes and vitamins at cellular level which prevent the occurrence of disease. However, factors tilting the balance in favour of excess free radicals generation lead to widespread oxidative tissue damage and diseases. Therefore, trouble starts when there is an excess of free radicals and the defence mechanism lags behind. Overwhelming production of free radicals in response to exposure to toxic chemicals and ageing may necessitate judicious antioxidant supplement to help alleviate free radical mediated damage.

Authors+Show Affiliations

M.L.N. Medical College, Allahabad.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9567509

Citation

Ansari, K N.. "The Free Radicals--the Hidden Culprits--an Update." Indian Journal of Medical Sciences, vol. 51, no. 9, 1997, pp. 319-36.
Ansari KN. The free radicals--the hidden culprits--an update. Indian J Med Sci. 1997;51(9):319-36.
Ansari, K. N. (1997). The free radicals--the hidden culprits--an update. Indian Journal of Medical Sciences, 51(9), pp. 319-36.
Ansari KN. The Free Radicals--the Hidden Culprits--an Update. Indian J Med Sci. 1997;51(9):319-36. PubMed PMID: 9567509.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The free radicals--the hidden culprits--an update. A1 - Ansari,K N, PY - 1998/5/6/pubmed PY - 1998/5/6/medline PY - 1998/5/6/entrez SP - 319 EP - 36 JF - Indian journal of medical sciences JO - Indian J Med Sci VL - 51 IS - 9 N2 - Free radicals are normally produced as a by-product of cellular metabolism. Free radicals are capable of killing bacteria, damage biomolecules, provoke immune response, activate oncogens, cause atherogenesis and enhance ageing process. However, in healthy conditions nature has endowed human body with enormous antioxidant potential. Subtle balance exists between free radical generation and antioxidant defence system to cope with oxidative stress by various enzymes and vitamins at cellular level which prevent the occurrence of disease. However, factors tilting the balance in favour of excess free radicals generation lead to widespread oxidative tissue damage and diseases. Therefore, trouble starts when there is an excess of free radicals and the defence mechanism lags behind. Overwhelming production of free radicals in response to exposure to toxic chemicals and ageing may necessitate judicious antioxidant supplement to help alleviate free radical mediated damage. SN - 0019-5359 UR - https://www.unboundmedicine.com/medline/citation/9567509/The_free_radicals__the_hidden_culprits__an_update_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -