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Postoperative pain control by single doses of piroxicam administered sublingually and aspirin.
J Marmara Univ Dent Fac. 1997 Sep; 2(4):658-64.JM

Abstract

The objective of this study is to evaluate and compare the analgesic efficacy of Piroxicam Fast Dissolving Dosage Formulation (FDDF) administered sublingually either preoperatively or postoperatively with that of aspirin and placebo. Hundred patients, undergoing surgical removal of mandibular third molars were given sublingually either piroxicam FDDF 40 mg or placebo or aspirin 500 mg according to a double blind experimental model. Pain scores and pain relief was recorded hourly for six hours following the operation. Rescue analgesics used during the trial and overall assessment of the drug were recorded at the end of six hours. Scores were evaluated statistically by student t test. Piroxicam FDDF was significantly (p < 0.05) more effective than aspirin and placebo for all variables, and less rescue analgesics were required in patients receiving piroxicam preoperatively. It was concluded that single doses of piroxicam FDDF administered sublingually either preoperatively or postoperatively appeared to be effective analgesic for the control of pain after third molar surgery with no side effects.

Authors+Show Affiliations

Gazi University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ankara, Türkiye.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

9569795

Citation

Alpaslan, C, et al. "Postoperative Pain Control By Single Doses of Piroxicam Administered Sublingually and Aspirin." Journal of Marmara University Dental Faculty, vol. 2, no. 4, 1997, pp. 658-64.
Alpaslan C, Alpaslan G, Uğar D. Postoperative pain control by single doses of piroxicam administered sublingually and aspirin. J Marmara Univ Dent Fac. 1997;2(4):658-64.
Alpaslan, C., Alpaslan, G., & Uğar, D. (1997). Postoperative pain control by single doses of piroxicam administered sublingually and aspirin. Journal of Marmara University Dental Faculty, 2(4), 658-64.
Alpaslan C, Alpaslan G, Uğar D. Postoperative Pain Control By Single Doses of Piroxicam Administered Sublingually and Aspirin. J Marmara Univ Dent Fac. 1997;2(4):658-64. PubMed PMID: 9569795.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postoperative pain control by single doses of piroxicam administered sublingually and aspirin. AU - Alpaslan,C, AU - Alpaslan,G, AU - Uğar,D, PY - 1998/5/7/pubmed PY - 1998/5/7/medline PY - 1998/5/7/entrez SP - 658 EP - 64 JF - Journal of Marmara University Dental Faculty JO - J Marmara Univ Dent Fac VL - 2 IS - 4 N2 - The objective of this study is to evaluate and compare the analgesic efficacy of Piroxicam Fast Dissolving Dosage Formulation (FDDF) administered sublingually either preoperatively or postoperatively with that of aspirin and placebo. Hundred patients, undergoing surgical removal of mandibular third molars were given sublingually either piroxicam FDDF 40 mg or placebo or aspirin 500 mg according to a double blind experimental model. Pain scores and pain relief was recorded hourly for six hours following the operation. Rescue analgesics used during the trial and overall assessment of the drug were recorded at the end of six hours. Scores were evaluated statistically by student t test. Piroxicam FDDF was significantly (p < 0.05) more effective than aspirin and placebo for all variables, and less rescue analgesics were required in patients receiving piroxicam preoperatively. It was concluded that single doses of piroxicam FDDF administered sublingually either preoperatively or postoperatively appeared to be effective analgesic for the control of pain after third molar surgery with no side effects. SN - 1018-5992 UR - https://www.unboundmedicine.com/medline/citation/9569795/Postoperative_pain_control_by_single_doses_of_piroxicam_administered_sublingually_and_aspirin_ DB - PRIME DP - Unbound Medicine ER -