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Haemostatic risk factors for cardiovascular diseases.
Eur Heart J 1998; 19 Suppl C:C39-43EH

Abstract

Strong evidence from large observational epidemiological studies links haemostatic variables to the future risk of myocardial infarction and stroke. Recent data provide further evidence for an early involvement of haemostatic parameters in atherosclerosis. So far, a variety of markers of a procoagulatory tendency e.g. elevated fibrinogen, coagulation factor VII, factor VIII and von Willebrand factor, platelet hyperaggregation, increased plasma levels of D-dimer, and decreased fibrinolytic capacity, e.g. characterized by increased levels of PAI-1 activity and decreased t-PA concentrations have been identified prospectively. Thus, a complex disturbed haemostatic system plays an important role in the development of atherothrombotic events in several vascular beds. This review discusses the epidemiologic evidence of the association between the haemostatic system and cardiovascular disease.

Authors+Show Affiliations

Abteilung Innere Medizin II-Kardiologie, Medizinische Universitätsklinik, Ulm, Germany.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9597424

Citation

Koenig, W. "Haemostatic Risk Factors for Cardiovascular Diseases." European Heart Journal, vol. 19 Suppl C, 1998, pp. C39-43.
Koenig W. Haemostatic risk factors for cardiovascular diseases. Eur Heart J. 1998;19 Suppl C:C39-43.
Koenig, W. (1998). Haemostatic risk factors for cardiovascular diseases. European Heart Journal, 19 Suppl C, pp. C39-43.
Koenig W. Haemostatic Risk Factors for Cardiovascular Diseases. Eur Heart J. 1998;19 Suppl C:C39-43. PubMed PMID: 9597424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Haemostatic risk factors for cardiovascular diseases. A1 - Koenig,W, PY - 1998/5/23/pubmed PY - 1998/5/23/medline PY - 1998/5/23/entrez SP - C39 EP - 43 JF - European heart journal JO - Eur. Heart J. VL - 19 Suppl C N2 - Strong evidence from large observational epidemiological studies links haemostatic variables to the future risk of myocardial infarction and stroke. Recent data provide further evidence for an early involvement of haemostatic parameters in atherosclerosis. So far, a variety of markers of a procoagulatory tendency e.g. elevated fibrinogen, coagulation factor VII, factor VIII and von Willebrand factor, platelet hyperaggregation, increased plasma levels of D-dimer, and decreased fibrinolytic capacity, e.g. characterized by increased levels of PAI-1 activity and decreased t-PA concentrations have been identified prospectively. Thus, a complex disturbed haemostatic system plays an important role in the development of atherothrombotic events in several vascular beds. This review discusses the epidemiologic evidence of the association between the haemostatic system and cardiovascular disease. SN - 0195-668X UR - https://www.unboundmedicine.com/medline/citation/9597424/Haemostatic_risk_factors_for_cardiovascular_diseases_ DB - PRIME DP - Unbound Medicine ER -