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Antifungal amide from leaves of Piper hispidum.
J Nat Prod. 1998 May; 61(5):637-9.JN

Abstract

Bioactivity-guided fractionation of a CH2Cl2 extract from leaves of Piper hispidum (Piperaceae) yielded a new pyrrolidine amide, N-[7-(3',4'-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl] pyrrolidine 1, in addition to two known amides N-[5-(3', 4'-methylenedioxyphenyl)-2(E)-pentadienoyl] pyrrolidine and N-[2-(3', 4'-methylenedioxy-6'-methoxyphenyl)-2(Z)-propenoyl]pyrrolidine. The structure of compound 1 was elucidated by interpretation of spectral data, including ES-MS. Compound 1 showed antifungal activity against Cladosporium sphaerospermum.

Authors+Show Affiliations

Alécio AC
Instituto de Química, Universidade Estadual Paulista, CP 355, 14800-900, Araraquara-SP, Brazil.
da Silva Bolzani V
No affiliation info available
Young MC
No affiliation info available
Kato MJ
No affiliation info available
Furlan M
No affiliation info available

MeSH

Antifungal AgentsCladosporiumPlant LeavesPlantsPyrrolidinesSpectrum Analysis

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9599264

Citation

Alécio, A C., et al. "Antifungal Amide From Leaves of Piper Hispidum." Journal of Natural Products, vol. 61, no. 5, 1998, pp. 637-9.
Alécio AC, da Silva Bolzani V, Young MC, et al. Antifungal amide from leaves of Piper hispidum. J Nat Prod. 1998;61(5):637-9.
Alécio, A. C., da Silva Bolzani, V., Young, M. C., Kato, M. J., & Furlan, M. (1998). Antifungal amide from leaves of Piper hispidum. Journal of Natural Products, 61(5), 637-9.
Alécio AC, et al. Antifungal Amide From Leaves of Piper Hispidum. J Nat Prod. 1998;61(5):637-9. PubMed PMID: 9599264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antifungal amide from leaves of Piper hispidum. AU - Alécio,A C, AU - da Silva Bolzani,V, AU - Young,M C, AU - Kato,M J, AU - Furlan,M, PY - 1998/6/4/pubmed PY - 1998/6/4/medline PY - 1998/6/4/entrez SP - 637 EP - 9 JF - Journal of natural products JO - J Nat Prod VL - 61 IS - 5 N2 - Bioactivity-guided fractionation of a CH2Cl2 extract from leaves of Piper hispidum (Piperaceae) yielded a new pyrrolidine amide, N-[7-(3',4'-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl] pyrrolidine 1, in addition to two known amides N-[5-(3', 4'-methylenedioxyphenyl)-2(E)-pentadienoyl] pyrrolidine and N-[2-(3', 4'-methylenedioxy-6'-methoxyphenyl)-2(Z)-propenoyl]pyrrolidine. The structure of compound 1 was elucidated by interpretation of spectral data, including ES-MS. Compound 1 showed antifungal activity against Cladosporium sphaerospermum. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/9599264/Antifungal_amide_from_leaves_of_Piper_hispidum_ L2 - https://doi.org/10.1021/np9703656 DB - PRIME DP - Unbound Medicine ER -