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The screening sensitivity of endoscopy, acid perfusion test and 24-hour pH-monitoring to evaluate esophagitis in patients with heartburn and histological esophagitis.
Arq Gastroenterol 1997 Jul-Sep; 34(3):148-56AG

Abstract

The sensitivity of endoscopic examinations, acid perfusion test and 24-hour esophageal pH-monitoring, were studied in patients with heartburn. Thirty six adult patients with histological esophagitis were included in this prospective study. Endoscopy showed esophageal lesion in 18/36 (sensitivity of 50%): esophagitis grade I in 10 (55.6%) and, grade II in eight (44.4%). Acid perfusion test was positive in 10/25 (sensitivity of 40%) of the patients submitted to the test. Twenty-four-hour pH-monitoring was positive in 17/29 patients (sensitivity of 58.6%): eight (61.5%) did not have esophageal lesion at endoscopy, two (25%) had esophagitis grade I and seven (87.5%) had esophagitis grade II. In the patients submitted to 24-hour pH-monitoring, a greater number or reflux episodes in orthostatic position than in supine position (P < 0.0001) was observed. The total number of reflux episodes, the most prolonged reflux and the total pH time < 4 were statistically higher in post-prandial period than during meals (P = 0.005).

Authors+Show Affiliations

Department of Gastroenterology, Medical School, University of São Paulo, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

9611292

Citation

Navarro-Rodriguez, T, et al. "The Screening Sensitivity of Endoscopy, Acid Perfusion Test and 24-hour pH-monitoring to Evaluate Esophagitis in Patients With Heartburn and Histological Esophagitis." Arquivos De Gastroenterologia, vol. 34, no. 3, 1997, pp. 148-56.
Navarro-Rodriguez T, de Moraes-Filho JP, Arakaki E, et al. The screening sensitivity of endoscopy, acid perfusion test and 24-hour pH-monitoring to evaluate esophagitis in patients with heartburn and histological esophagitis. Arq Gastroenterol. 1997;34(3):148-56.
Navarro-Rodriguez, T., de Moraes-Filho, J. P., Arakaki, E., Chinzon, D., Zaterka, S., Iriya, K., & Laudanna, A. A. (1997). The screening sensitivity of endoscopy, acid perfusion test and 24-hour pH-monitoring to evaluate esophagitis in patients with heartburn and histological esophagitis. Arquivos De Gastroenterologia, 34(3), pp. 148-56.
Navarro-Rodriguez T, et al. The Screening Sensitivity of Endoscopy, Acid Perfusion Test and 24-hour pH-monitoring to Evaluate Esophagitis in Patients With Heartburn and Histological Esophagitis. Arq Gastroenterol. 1997;34(3):148-56. PubMed PMID: 9611292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The screening sensitivity of endoscopy, acid perfusion test and 24-hour pH-monitoring to evaluate esophagitis in patients with heartburn and histological esophagitis. AU - Navarro-Rodriguez,T, AU - de Moraes-Filho,J P, AU - Arakaki,E, AU - Chinzon,D, AU - Zaterka,S, AU - Iriya,K, AU - Laudanna,A A, PY - 1997/7/1/pubmed PY - 1998/6/5/medline PY - 1997/7/1/entrez SP - 148 EP - 56 JF - Arquivos de gastroenterologia JO - Arq Gastroenterol VL - 34 IS - 3 N2 - The sensitivity of endoscopic examinations, acid perfusion test and 24-hour esophageal pH-monitoring, were studied in patients with heartburn. Thirty six adult patients with histological esophagitis were included in this prospective study. Endoscopy showed esophageal lesion in 18/36 (sensitivity of 50%): esophagitis grade I in 10 (55.6%) and, grade II in eight (44.4%). Acid perfusion test was positive in 10/25 (sensitivity of 40%) of the patients submitted to the test. Twenty-four-hour pH-monitoring was positive in 17/29 patients (sensitivity of 58.6%): eight (61.5%) did not have esophageal lesion at endoscopy, two (25%) had esophagitis grade I and seven (87.5%) had esophagitis grade II. In the patients submitted to 24-hour pH-monitoring, a greater number or reflux episodes in orthostatic position than in supine position (P < 0.0001) was observed. The total number of reflux episodes, the most prolonged reflux and the total pH time < 4 were statistically higher in post-prandial period than during meals (P = 0.005). SN - 0004-2803 UR - https://www.unboundmedicine.com/medline/citation/9611292/The_screening_sensitivity_of_endoscopy_acid_perfusion_test_and_24_hour_pH_monitoring_to_evaluate_esophagitis_in_patients_with_heartburn_and_histological_esophagitis_ L2 - https://medlineplus.gov/heartburn.html DB - PRIME DP - Unbound Medicine ER -