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Gastroduodenal mucosa in peptic ulcer: endoscopic and histological assessment.
Trop Gastroenterol. 1997 Oct-Dec; 18(4):156-9.TG

Abstract

This study aimed to assess the prevalence of endoscopic and histological gastroduodenitis as well as helicobacter-like organisms in patients with peptic ulcer. After diagnostic endoscopy, gastroduodenal biopsy specimens were taken from thirty patients (n = 30) with clinical and endoscopic diagnosis of peptic ulcer (duodenal ulcer = 25, gastric ulcer = 5). Endoscopic gastroduodenitis occurred in 18 patients (60%). Histological gastritis was detected in the gastric body or antrum in 25 (83%) and duodenitis in 17 (57%) patients. There was significant correlation between endoscopic and histological gastritis (p < 0.05). Helicobacter-like organisms occurred in 73% of the patients with peptic ulcer and in 88% of the antral biopsy specimens showing antral gastritis. Presence of helicobacter-like organisms was in particular associated with acute on chronic gastritis compared to chronic gastritis (p < 0.01). Moreover the patients with gastritis were found to belong to the older age group and 81.8% had blood group O +ve (p < 0.01 and p < 0.05 respectively). We conclude that presence of helicobacter-like organisms in patients with peptic ulcer is significantly associated with acute on chronic gastritis.

Authors+Show Affiliations

Medical College Hospital, Calcutta, India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9612096

Citation

Chattopadhyay, G, et al. "Gastroduodenal Mucosa in Peptic Ulcer: Endoscopic and Histological Assessment." Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation, vol. 18, no. 4, 1997, pp. 156-9.
Chattopadhyay G, Basu K, Mukherjee S, et al. Gastroduodenal mucosa in peptic ulcer: endoscopic and histological assessment. Trop Gastroenterol. 1997;18(4):156-9.
Chattopadhyay, G., Basu, K., Mukherjee, S., & Hazra, B. R. (1997). Gastroduodenal mucosa in peptic ulcer: endoscopic and histological assessment. Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation, 18(4), 156-9.
Chattopadhyay G, et al. Gastroduodenal Mucosa in Peptic Ulcer: Endoscopic and Histological Assessment. Trop Gastroenterol. 1997 Oct-Dec;18(4):156-9. PubMed PMID: 9612096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastroduodenal mucosa in peptic ulcer: endoscopic and histological assessment. AU - Chattopadhyay,G, AU - Basu,K, AU - Mukherjee,S, AU - Hazra,B R, PY - 1998/6/5/pubmed PY - 1998/6/5/medline PY - 1998/6/5/entrez SP - 156 EP - 9 JF - Tropical gastroenterology : official journal of the Digestive Diseases Foundation JO - Trop Gastroenterol VL - 18 IS - 4 N2 - This study aimed to assess the prevalence of endoscopic and histological gastroduodenitis as well as helicobacter-like organisms in patients with peptic ulcer. After diagnostic endoscopy, gastroduodenal biopsy specimens were taken from thirty patients (n = 30) with clinical and endoscopic diagnosis of peptic ulcer (duodenal ulcer = 25, gastric ulcer = 5). Endoscopic gastroduodenitis occurred in 18 patients (60%). Histological gastritis was detected in the gastric body or antrum in 25 (83%) and duodenitis in 17 (57%) patients. There was significant correlation between endoscopic and histological gastritis (p < 0.05). Helicobacter-like organisms occurred in 73% of the patients with peptic ulcer and in 88% of the antral biopsy specimens showing antral gastritis. Presence of helicobacter-like organisms was in particular associated with acute on chronic gastritis compared to chronic gastritis (p < 0.01). Moreover the patients with gastritis were found to belong to the older age group and 81.8% had blood group O +ve (p < 0.01 and p < 0.05 respectively). We conclude that presence of helicobacter-like organisms in patients with peptic ulcer is significantly associated with acute on chronic gastritis. SN - 0250-636X UR - https://www.unboundmedicine.com/medline/citation/9612096/Gastroduodenal_mucosa_in_peptic_ulcer:_endoscopic_and_histological_assessment_ L2 - https://medlineplus.gov/helicobacterpyloriinfections.html DB - PRIME DP - Unbound Medicine ER -