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Role of viruses in middle-ear disease.
Ann N Y Acad Sci. 1997 Dec 29; 830:143-57.AN

Abstract

Taken together, there is ample evidence suggesting a role for viruses in the pathogenesis of OM. This evidence comes from numerous studies performed in animals and in vitro cell cultures, as well as in adults and children with URI and OM. Viruses induce host immune and inflammatory responses that result in pathology of the ET and the middle ear, and predispose the host in various ways to secondary bacterial infection. A suggested mechanism for the pathogenesis of OM following respiratory viral infection is presented in Figure 1.

Authors+Show Affiliations

Department of Pediatrics, University of Texas Medical Branch, Galveston 77555-0371, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

9616674

Citation

Chonmaitree, T, and T Heikkinen. "Role of Viruses in Middle-ear Disease." Annals of the New York Academy of Sciences, vol. 830, 1997, pp. 143-57.
Chonmaitree T, Heikkinen T. Role of viruses in middle-ear disease. Ann N Y Acad Sci. 1997;830:143-57.
Chonmaitree, T., & Heikkinen, T. (1997). Role of viruses in middle-ear disease. Annals of the New York Academy of Sciences, 830, 143-57.
Chonmaitree T, Heikkinen T. Role of Viruses in Middle-ear Disease. Ann N Y Acad Sci. 1997 Dec 29;830:143-57. PubMed PMID: 9616674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of viruses in middle-ear disease. AU - Chonmaitree,T, AU - Heikkinen,T, PY - 1998/6/9/pubmed PY - 1998/6/9/medline PY - 1998/6/9/entrez SP - 143 EP - 57 JF - Annals of the New York Academy of Sciences JO - Ann N Y Acad Sci VL - 830 N2 - Taken together, there is ample evidence suggesting a role for viruses in the pathogenesis of OM. This evidence comes from numerous studies performed in animals and in vitro cell cultures, as well as in adults and children with URI and OM. Viruses induce host immune and inflammatory responses that result in pathology of the ET and the middle ear, and predispose the host in various ways to secondary bacterial infection. A suggested mechanism for the pathogenesis of OM following respiratory viral infection is presented in Figure 1. SN - 0077-8923 UR - https://www.unboundmedicine.com/medline/citation/9616674/Role_of_viruses_in_middle_ear_disease_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=1997&volume=830&spage=143 DB - PRIME DP - Unbound Medicine ER -