Tags

Type your tag names separated by a space and hit enter

Relationship between hunger-satiety feelings and various metabolic parameters in women with obesity during controlled weight loss.
Obes Res 1998; 6(3):225-30OR

Abstract

OBJECTIVE

Satiety plays an important role in weight control. The meaning of fasting hormone levels and satiety feelings, and how post-absorptive changes after meals high in carbohydrate regulate appetite remains to be demonstrated.

RESEARCH METHODS AND PROCEDURES

Prospective metabolic study with 25 non-diabetic obese women at the Energy Metabolism Research Unit of the Department of Nutrition Sciences, University of Alabama at Birmingham. We analyzed fasting and postprandial ratings of hunger-satiety and values of various metabolic parameters (serum glucose and insulin, plasma cholecystokinin, respiratory quotient) during controlled weight loss. The postprandial measures were assessed following a test meal providing 320 kcal and yielding a food quotient of 0.89.

RESULTS

In the fasting state, there was no correlation between hunger-satiety ratings and any of the measured metabolic parameters. Under postprandial conditions, satiety was positively related to glucose (p=0.002) and insulin (p=0.002) responses to the test meal. In multivariate analysis including glucose, insulin, cholecystokinin, hunger-satiety ratings and respiratory quotient, insulin was the only independent predictor of satiety in the postprandial state.

DISCUSSION

These data suggest an association between the endogenous insulin response and feelings of postprandial satiety. Insulin's satiation properties, which could well be mediated by other hormones, may represent a primary factor of food intake regulation after meals relatively high in carbohydrate.

Authors+Show Affiliations

Department of Nutrition Sciences, University of Alabama at Birmingham, 35294, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9618127

Citation

Heini, A F., et al. "Relationship Between Hunger-satiety Feelings and Various Metabolic Parameters in Women With Obesity During Controlled Weight Loss." Obesity Research, vol. 6, no. 3, 1998, pp. 225-30.
Heini AF, Kirk KA, Lara-Castro C, et al. Relationship between hunger-satiety feelings and various metabolic parameters in women with obesity during controlled weight loss. Obes Res. 1998;6(3):225-30.
Heini, A. F., Kirk, K. A., Lara-Castro, C., & Weinsier, R. L. (1998). Relationship between hunger-satiety feelings and various metabolic parameters in women with obesity during controlled weight loss. Obesity Research, 6(3), pp. 225-30.
Heini AF, et al. Relationship Between Hunger-satiety Feelings and Various Metabolic Parameters in Women With Obesity During Controlled Weight Loss. Obes Res. 1998;6(3):225-30. PubMed PMID: 9618127.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between hunger-satiety feelings and various metabolic parameters in women with obesity during controlled weight loss. AU - Heini,A F, AU - Kirk,K A, AU - Lara-Castro,C, AU - Weinsier,R L, PY - 1998/6/9/pubmed PY - 1998/6/9/medline PY - 1998/6/9/entrez SP - 225 EP - 30 JF - Obesity research JO - Obes. Res. VL - 6 IS - 3 N2 - OBJECTIVE: Satiety plays an important role in weight control. The meaning of fasting hormone levels and satiety feelings, and how post-absorptive changes after meals high in carbohydrate regulate appetite remains to be demonstrated. RESEARCH METHODS AND PROCEDURES: Prospective metabolic study with 25 non-diabetic obese women at the Energy Metabolism Research Unit of the Department of Nutrition Sciences, University of Alabama at Birmingham. We analyzed fasting and postprandial ratings of hunger-satiety and values of various metabolic parameters (serum glucose and insulin, plasma cholecystokinin, respiratory quotient) during controlled weight loss. The postprandial measures were assessed following a test meal providing 320 kcal and yielding a food quotient of 0.89. RESULTS: In the fasting state, there was no correlation between hunger-satiety ratings and any of the measured metabolic parameters. Under postprandial conditions, satiety was positively related to glucose (p=0.002) and insulin (p=0.002) responses to the test meal. In multivariate analysis including glucose, insulin, cholecystokinin, hunger-satiety ratings and respiratory quotient, insulin was the only independent predictor of satiety in the postprandial state. DISCUSSION: These data suggest an association between the endogenous insulin response and feelings of postprandial satiety. Insulin's satiation properties, which could well be mediated by other hormones, may represent a primary factor of food intake regulation after meals relatively high in carbohydrate. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/9618127/Relationship_between_hunger_satiety_feelings_and_various_metabolic_parameters_in_women_with_obesity_during_controlled_weight_loss_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1071-7323&date=1998&volume=6&issue=3&spage=225 DB - PRIME DP - Unbound Medicine ER -