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Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study.
J Bone Miner Res. 1998 Jun; 13(6):918-24.JB

Abstract

This prospective population-based study assessed predictors of hip fracture risk in white men. Participants were members of the Epidemiologic Follow-up Study cohort of the First National Health and Nutrition Examination Survey, a nationally representative sample of noninstitutionalized civilians who were followed for a maximum of 22 years. A cohort of 2879 white men (2249 in the nutrition and weight-loss subsample, 1437 in the bone density subsample) aged 45-74 years at baseline (1971-1975) were observed through 1992. Ninety-four percent of the original cohort were successfully traced. Hospital records and death certificates were used to identify a total of 71 hip fracture cases (61 in the nutrition and weight-loss subsample, 26 in the bone-density subsample). Among the factors evaluated were age at baseline, previous fractures other than hip, body mass index, smoking status, alcohol consumption, nonrecreational physical activity, weight loss from maximum, calcium intake, number of calories, protein consumption, chronic disease prevalence, and phalangeal bone density. The risk adjusted relative risk (RR) of hip fracture was significantly associated with presence of one or more chronic conditions (RR = 1.91, 95% confidence interval [CI] = 1.19-3.06), weight loss from maximum > or = 10% (RR = 2.27, 95% CI 1.13-4.59), and 1 SD change in phalangeal bone density (RR = 1.73, 95% CI 1.11-2.68). No other variables were significantly related to hip fracture risk. Although based on a small number of cases, this is one of the first prospective studies to relate weight loss and bone density to hip fracture risk in men.

Authors+Show Affiliations

Centers for Disease Control and Prevention, Hyattsville, Maryland, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9626622

Citation

Mussolino, M E., et al. "Risk Factors for Hip Fracture in White Men: the NHANES I Epidemiologic Follow-up Study." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, vol. 13, no. 6, 1998, pp. 918-24.
Mussolino ME, Looker AC, Madans JH, et al. Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study. J Bone Miner Res. 1998;13(6):918-24.
Mussolino, M. E., Looker, A. C., Madans, J. H., Langlois, J. A., & Orwoll, E. S. (1998). Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 13(6), 918-24.
Mussolino ME, et al. Risk Factors for Hip Fracture in White Men: the NHANES I Epidemiologic Follow-up Study. J Bone Miner Res. 1998;13(6):918-24. PubMed PMID: 9626622.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study. AU - Mussolino,M E, AU - Looker,A C, AU - Madans,J H, AU - Langlois,J A, AU - Orwoll,E S, PY - 1998/6/17/pubmed PY - 1998/6/17/medline PY - 1998/6/17/entrez SP - 918 EP - 24 JF - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research JO - J Bone Miner Res VL - 13 IS - 6 N2 - This prospective population-based study assessed predictors of hip fracture risk in white men. Participants were members of the Epidemiologic Follow-up Study cohort of the First National Health and Nutrition Examination Survey, a nationally representative sample of noninstitutionalized civilians who were followed for a maximum of 22 years. A cohort of 2879 white men (2249 in the nutrition and weight-loss subsample, 1437 in the bone density subsample) aged 45-74 years at baseline (1971-1975) were observed through 1992. Ninety-four percent of the original cohort were successfully traced. Hospital records and death certificates were used to identify a total of 71 hip fracture cases (61 in the nutrition and weight-loss subsample, 26 in the bone-density subsample). Among the factors evaluated were age at baseline, previous fractures other than hip, body mass index, smoking status, alcohol consumption, nonrecreational physical activity, weight loss from maximum, calcium intake, number of calories, protein consumption, chronic disease prevalence, and phalangeal bone density. The risk adjusted relative risk (RR) of hip fracture was significantly associated with presence of one or more chronic conditions (RR = 1.91, 95% confidence interval [CI] = 1.19-3.06), weight loss from maximum > or = 10% (RR = 2.27, 95% CI 1.13-4.59), and 1 SD change in phalangeal bone density (RR = 1.73, 95% CI 1.11-2.68). No other variables were significantly related to hip fracture risk. Although based on a small number of cases, this is one of the first prospective studies to relate weight loss and bone density to hip fracture risk in men. SN - 0884-0431 UR - https://www.unboundmedicine.com/medline/citation/9626622/Risk_factors_for_hip_fracture_in_white_men:_the_NHANES_I_Epidemiologic_Follow_up_Study_ L2 - https://doi.org/10.1359/jbmr.1998.13.6.918 DB - PRIME DP - Unbound Medicine ER -