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Lupin alkaloids from teratogenic and nonteratogenic lupins. IV. Concentration of total alkaloids, individual major alkaloids, and the teratogen anagyrine as a function of plant part and stage of growth and their relationship to crooked calf disease.
J Toxicol Environ Health. 1976 Jul; 1(6):899-908.JT

Abstract

The concentrations of total alkaloids and individual major alkaloids including the teratogen anagyrine were measured in various plant parts of teratogenic lupins as the plants matured. All alkaloids including angyrine were high in concentration in above-ground parts early in growth and decreased as plants matured, except for an increase in mature, intact seeds. Seeds were highest, followed by early growth leaves and stems. Roots were lowest with mature leaves and stems only slightly higher. Pregnant cows have the greatest risk of giving birth to calves with crooked calf disease when the concentration of the teratogen anagyrine is highest and the cows are in the susceptible 40-75 day gestation period when ingesting the plant.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

966319

Citation

Keeler, R F., et al. "Lupin Alkaloids From Teratogenic and Nonteratogenic Lupins. IV. Concentration of Total Alkaloids, Individual Major Alkaloids, and the Teratogen Anagyrine as a Function of Plant Part and Stage of Growth and Their Relationship to Crooked Calf Disease." Journal of Toxicology and Environmental Health, vol. 1, no. 6, 1976, pp. 899-908.
Keeler RF, Cronin EH, Shupe JL. Lupin alkaloids from teratogenic and nonteratogenic lupins. IV. Concentration of total alkaloids, individual major alkaloids, and the teratogen anagyrine as a function of plant part and stage of growth and their relationship to crooked calf disease. J Toxicol Environ Health. 1976;1(6):899-908.
Keeler, R. F., Cronin, E. H., & Shupe, J. L. (1976). Lupin alkaloids from teratogenic and nonteratogenic lupins. IV. Concentration of total alkaloids, individual major alkaloids, and the teratogen anagyrine as a function of plant part and stage of growth and their relationship to crooked calf disease. Journal of Toxicology and Environmental Health, 1(6), 899-908.
Keeler RF, Cronin EH, Shupe JL. Lupin Alkaloids From Teratogenic and Nonteratogenic Lupins. IV. Concentration of Total Alkaloids, Individual Major Alkaloids, and the Teratogen Anagyrine as a Function of Plant Part and Stage of Growth and Their Relationship to Crooked Calf Disease. J Toxicol Environ Health. 1976;1(6):899-908. PubMed PMID: 966319.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lupin alkaloids from teratogenic and nonteratogenic lupins. IV. Concentration of total alkaloids, individual major alkaloids, and the teratogen anagyrine as a function of plant part and stage of growth and their relationship to crooked calf disease. AU - Keeler,R F, AU - Cronin,E H, AU - Shupe,J L, PY - 1976/7/1/pubmed PY - 1976/7/1/medline PY - 1976/7/1/entrez SP - 899 EP - 908 JF - Journal of toxicology and environmental health JO - J Toxicol Environ Health VL - 1 IS - 6 N2 - The concentrations of total alkaloids and individual major alkaloids including the teratogen anagyrine were measured in various plant parts of teratogenic lupins as the plants matured. All alkaloids including angyrine were high in concentration in above-ground parts early in growth and decreased as plants matured, except for an increase in mature, intact seeds. Seeds were highest, followed by early growth leaves and stems. Roots were lowest with mature leaves and stems only slightly higher. Pregnant cows have the greatest risk of giving birth to calves with crooked calf disease when the concentration of the teratogen anagyrine is highest and the cows are in the susceptible 40-75 day gestation period when ingesting the plant. SN - 0098-4108 UR - https://www.unboundmedicine.com/medline/citation/966319/Lupin_alkaloids_from_teratogenic_and_nonteratogenic_lupins__IV__Concentration_of_total_alkaloids_individual_major_alkaloids_and_the_teratogen_anagyrine_as_a_function_of_plant_part_and_stage_of_growth_and_their_relationship_to_crooked_calf_disease_ DB - PRIME DP - Unbound Medicine ER -