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Prenatal exposure to cocaine and other drugs. Outcome at four to six years.
Ann N Y Acad Sci. 1998 Jun 21; 846:314-28.AN

Abstract

In a longitudinal, prospective study, 95 children born to mothers who used cocaine and other drugs during pregnancy and 75 matched, nonexposed children born to mothers who had no evidence of alcohol or illicit substance use during pregnancy were evaluated for cognitive and behavioral outcome at 6 years of age. Prenatal exposure to cocaine and other drugs had no direct effect on the child's cognitive outcome (measured as IQ), but it had an indirect effect as mediated through the home environment. However, prenatal exposure to cocaine and other drugs did have a direct effect on the child's behavioral characteristics at 4-6 years of age, with the home environment having little impact. This study helps us to understand the fragile interaction of biological and environmental factors affecting the cognitive and behavioral development of children prenatally exposed to cocaine and other drugs.

Authors+Show Affiliations

National Association for Families and Addiction Research and Education, Chicago, Illinois 60603, USA. irajc@smtp.bmai.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

9668418

Citation

Chasnoff, I J., et al. "Prenatal Exposure to Cocaine and Other Drugs. Outcome at Four to Six Years." Annals of the New York Academy of Sciences, vol. 846, 1998, pp. 314-28.
Chasnoff IJ, Anson A, Hatcher R, et al. Prenatal exposure to cocaine and other drugs. Outcome at four to six years. Ann N Y Acad Sci. 1998;846:314-28.
Chasnoff, I. J., Anson, A., Hatcher, R., Stenson, H., Iaukea, K., & Randolph, L. A. (1998). Prenatal exposure to cocaine and other drugs. Outcome at four to six years. Annals of the New York Academy of Sciences, 846, 314-28.
Chasnoff IJ, et al. Prenatal Exposure to Cocaine and Other Drugs. Outcome at Four to Six Years. Ann N Y Acad Sci. 1998 Jun 21;846:314-28. PubMed PMID: 9668418.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prenatal exposure to cocaine and other drugs. Outcome at four to six years. AU - Chasnoff,I J, AU - Anson,A, AU - Hatcher,R, AU - Stenson,H, AU - Iaukea,K, AU - Randolph,L A, PY - 1998/7/21/pubmed PY - 1998/7/21/medline PY - 1998/7/21/entrez SP - 314 EP - 28 JF - Annals of the New York Academy of Sciences JO - Ann N Y Acad Sci VL - 846 N2 - In a longitudinal, prospective study, 95 children born to mothers who used cocaine and other drugs during pregnancy and 75 matched, nonexposed children born to mothers who had no evidence of alcohol or illicit substance use during pregnancy were evaluated for cognitive and behavioral outcome at 6 years of age. Prenatal exposure to cocaine and other drugs had no direct effect on the child's cognitive outcome (measured as IQ), but it had an indirect effect as mediated through the home environment. However, prenatal exposure to cocaine and other drugs did have a direct effect on the child's behavioral characteristics at 4-6 years of age, with the home environment having little impact. This study helps us to understand the fragile interaction of biological and environmental factors affecting the cognitive and behavioral development of children prenatally exposed to cocaine and other drugs. SN - 0077-8923 UR - https://www.unboundmedicine.com/medline/citation/9668418/Prenatal_exposure_to_cocaine_and_other_drugs__Outcome_at_four_to_six_years_ DB - PRIME DP - Unbound Medicine ER -