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[Evaluation of the risk of neuropsychological damage from lead exposure in childhood].
Ann Ist Super Sanita. 1998; 34(1):97-104.AI

Abstract

Potential neurotoxicity of lead in children has been explored in many recent epidemiological studies carried out all over the world. Within a multicentric European study, an investigation was carried out also in Italy on children living in an industrial area and characterised by a non steady-state exposure condition with higher exposure at the early stages of life. This peculiar feature allowed to observe interesting associations between neurobehavioural functions and the levels of Pb measured in teeth, but not in blood. Indeed, Pb in teeth was associated with the results of psychometric tests which evaluate the discriminant ability and the attention. Other associations, like those found between the intelligence quotient (IQ) scores and Pb in teeth disappeared after correction for the socioeconomical status of parents. In general, in children exposed to environmental Pb, more consistent associations were found with visual-motor integration and attention than with IQ measurements. In agreement with literature data from other countries, we suggest that the relevance of neurotoxic effects of Pb is limited, at least at the current exposure levels, but also that a threshold Pb level associated with no effect cannot be identified.

Authors+Show Affiliations

Dipartimento di Scienze Biomediche, Università degli Studi, Modena.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

9679346

Citation

Borella, P, et al. "[Evaluation of the Risk of Neuropsychological Damage From Lead Exposure in Childhood]." Annali dell'Istituto Superiore Di Sanita, vol. 34, no. 1, 1998, pp. 97-104.
Borella P, Sturloni N, Rovesti S, et al. [Evaluation of the risk of neuropsychological damage from lead exposure in childhood]. Ann Ist Super Sanita. 1998;34(1):97-104.
Borella, P., Sturloni, N., Rovesti, S., Vivoli, R., Bargellini, A., & Vivoli, G. (1998). [Evaluation of the risk of neuropsychological damage from lead exposure in childhood]. Annali dell'Istituto Superiore Di Sanita, 34(1), 97-104.
Borella P, et al. [Evaluation of the Risk of Neuropsychological Damage From Lead Exposure in Childhood]. Ann Ist Super Sanita. 1998;34(1):97-104. PubMed PMID: 9679346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of the risk of neuropsychological damage from lead exposure in childhood]. AU - Borella,P, AU - Sturloni,N, AU - Rovesti,S, AU - Vivoli,R, AU - Bargellini,A, AU - Vivoli,G, PY - 1998/7/29/pubmed PY - 1998/7/29/medline PY - 1998/7/29/entrez SP - 97 EP - 104 JF - Annali dell'Istituto superiore di sanita JO - Ann Ist Super Sanita VL - 34 IS - 1 N2 - Potential neurotoxicity of lead in children has been explored in many recent epidemiological studies carried out all over the world. Within a multicentric European study, an investigation was carried out also in Italy on children living in an industrial area and characterised by a non steady-state exposure condition with higher exposure at the early stages of life. This peculiar feature allowed to observe interesting associations between neurobehavioural functions and the levels of Pb measured in teeth, but not in blood. Indeed, Pb in teeth was associated with the results of psychometric tests which evaluate the discriminant ability and the attention. Other associations, like those found between the intelligence quotient (IQ) scores and Pb in teeth disappeared after correction for the socioeconomical status of parents. In general, in children exposed to environmental Pb, more consistent associations were found with visual-motor integration and attention than with IQ measurements. In agreement with literature data from other countries, we suggest that the relevance of neurotoxic effects of Pb is limited, at least at the current exposure levels, but also that a threshold Pb level associated with no effect cannot be identified. SN - 0021-2571 UR - https://www.unboundmedicine.com/medline/citation/9679346/[Evaluation_of_the_risk_of_neuropsychological_damage_from_lead_exposure_in_childhood]_ L2 - https://medlineplus.gov/leadpoisoning.html DB - PRIME DP - Unbound Medicine ER -