Tags

Type your tag names separated by a space and hit enter

Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid.

Abstract

Three diets containing either borage oil (BO) and southern hemisphere fish oil Marinol (MO), or BO and tuna orbital oil (TO), or a northern hemisphere fish oil (FO) were fed to duplicate groups of turbot (Scophthalmus maximus) of initial mean weight 1.2 g for a period of 12 weeks. The BO/MO and BO/TO diets were enriched in gamma-linolenic (18:3n-6, GLA) and eicosapentaenoic (20:5n-3, EPA) acids, and GLA and docosahexaenoic acid (22:6n-3, DHA), respectively. No differences were observed in final weights or growth rates, either between duplicate tanks or between dietary treatments. Half of the FO-fed fish sampled showed a histopathological lesion indicative of lipoid liver degeneration while the other treatments only showed a slight incidence of the same pathology. The fatty acid compositions of carcass and tissues broadly reflected the dietary input. In general, fish fed the BO/MO diet had increased levels of 18:2n-6, 18:3n-6, 20:3n-6 and 20:5n-3, but a lower level of 22:6n-3, compared to fish fed FO. In fish fed the BO/TO diet, levels of 18:2n-6, 18:3n-6, 20:3n-6 and 20:4n-6 were increased while levels of 20:5n-3 and 22:5n-3 were reduced, compared to fish fed FO. Concentrations of thromboxanes B (TXB) and leukotrienes B (LTB), derived from 20:4n-6 and 20:5n-3, were measured in plasma and stimulated blood cells. Levels of TXB2 were greatest in fish fed the BO/TO diet compared to both other treatments, while LTB4 was decreased in fish fed the BO/MO diet compared to both other treatments. In a stress test which involved anaesthesia followed by measurement of recovery times, fish fed the BO/MO diet had significantly lower recovery times compared to fish fed the FO diet.

Authors+Show Affiliations

Department of Biological and Molecular Sciences, University of Stirling, UK.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9690713

Citation

Bell, J G., et al. "Growth, Mortality, Tissue Histopathology and Fatty Acid Compositions, Eicosanoid Production and Response to Stress, in Juvenile Turbot Fed Diets Rich in Gamma-linolenic Acid in Combination With Eicosapentaenoic Acid or Docosahexaenoic Acid." Prostaglandins, Leukotrienes, and Essential Fatty Acids, vol. 58, no. 5, 1998, pp. 353-64.
Bell JG, Tocher DR, Farndale BM, et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. Prostaglandins Leukot Essent Fatty Acids. 1998;58(5):353-64.
Bell, J. G., Tocher, D. R., Farndale, B. M., & Sargent, J. R. (1998). Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 58(5), pp. 353-64.
Bell JG, et al. Growth, Mortality, Tissue Histopathology and Fatty Acid Compositions, Eicosanoid Production and Response to Stress, in Juvenile Turbot Fed Diets Rich in Gamma-linolenic Acid in Combination With Eicosapentaenoic Acid or Docosahexaenoic Acid. Prostaglandins Leukot Essent Fatty Acids. 1998;58(5):353-64. PubMed PMID: 9690713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. AU - Bell,J G, AU - Tocher,D R, AU - Farndale,B M, AU - Sargent,J R, PY - 1998/8/5/pubmed PY - 1998/8/5/medline PY - 1998/8/5/entrez SP - 353 EP - 64 JF - Prostaglandins, leukotrienes, and essential fatty acids JO - Prostaglandins Leukot. Essent. Fatty Acids VL - 58 IS - 5 N2 - Three diets containing either borage oil (BO) and southern hemisphere fish oil Marinol (MO), or BO and tuna orbital oil (TO), or a northern hemisphere fish oil (FO) were fed to duplicate groups of turbot (Scophthalmus maximus) of initial mean weight 1.2 g for a period of 12 weeks. The BO/MO and BO/TO diets were enriched in gamma-linolenic (18:3n-6, GLA) and eicosapentaenoic (20:5n-3, EPA) acids, and GLA and docosahexaenoic acid (22:6n-3, DHA), respectively. No differences were observed in final weights or growth rates, either between duplicate tanks or between dietary treatments. Half of the FO-fed fish sampled showed a histopathological lesion indicative of lipoid liver degeneration while the other treatments only showed a slight incidence of the same pathology. The fatty acid compositions of carcass and tissues broadly reflected the dietary input. In general, fish fed the BO/MO diet had increased levels of 18:2n-6, 18:3n-6, 20:3n-6 and 20:5n-3, but a lower level of 22:6n-3, compared to fish fed FO. In fish fed the BO/TO diet, levels of 18:2n-6, 18:3n-6, 20:3n-6 and 20:4n-6 were increased while levels of 20:5n-3 and 22:5n-3 were reduced, compared to fish fed FO. Concentrations of thromboxanes B (TXB) and leukotrienes B (LTB), derived from 20:4n-6 and 20:5n-3, were measured in plasma and stimulated blood cells. Levels of TXB2 were greatest in fish fed the BO/TO diet compared to both other treatments, while LTB4 was decreased in fish fed the BO/MO diet compared to both other treatments. In a stress test which involved anaesthesia followed by measurement of recovery times, fish fed the BO/MO diet had significantly lower recovery times compared to fish fed the FO diet. SN - 0952-3278 UR - https://www.unboundmedicine.com/medline/citation/9690713/Growth_mortality_tissue_histopathology_and_fatty_acid_compositions_eicosanoid_production_and_response_to_stress_in_juvenile_turbot_fed_diets_rich_in_gamma_linolenic_acid_in_combination_with_eicosapentaenoic_acid_or_docosahexaenoic_acid_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0952-3278(98)90071-0 DB - PRIME DP - Unbound Medicine ER -