Tags

Type your tag names separated by a space and hit enter

The association between vasectomy and prostate cancer: a systematic review of the literature.
Fertil Steril 1998; 70(2):191-200FS

Abstract

OBJECTIVE

To evaluate the possible association between vasectomy and prostate cancer.

DESIGN

Systematic review of the literature.

PATIENT(S)

Fourteen original studies published between January 1985 and December 1996 that addressed the association between vasectomy and prostate cancer.

MAIN OUTCOME MEASURE(S)

The strength of the association was estimated with the use of a meta-analysis (DerSimonian and Laird method). A sensitivity analysis was conducted to assess the impact of different sources of heterogeneity.

RESULT(S)

Fourteen original papers were reviewed (5 cohort and 9 case-control studies). Relative risks ranged between 0.44 (95% confidence interval [CI] = 0.1-4.0) and 6.70 (95% CI = 2.1-21.6). The overall relative risk (DerSimonian and Laird estimate) was 1.23 (95% CI = 1.01-1.49). The sensitivity analysis showed that this measure was very sensitive to the study base, the type of design used, and the possibility of bias. Further, the funnel plot demonstrated the probable existence of publication bias.

CONCLUSION(S)

No causal association was found between vasectomy and prostate cancer. Individuals who have undergone vasectomy are not at high risk for the development of prostate cancer.

Authors+Show Affiliations

Department of Preventive and Social Medicine, Faculty of Medicine, University of Zaragoza, Spain. APT@OMC.TELPROF.ESNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review

Language

eng

PubMed ID

9696205

Citation

Bernal-Delgado, E, et al. "The Association Between Vasectomy and Prostate Cancer: a Systematic Review of the Literature." Fertility and Sterility, vol. 70, no. 2, 1998, pp. 191-200.
Bernal-Delgado E, Latour-Pérez J, Pradas-Arnal F, et al. The association between vasectomy and prostate cancer: a systematic review of the literature. Fertil Steril. 1998;70(2):191-200.
Bernal-Delgado, E., Latour-Pérez, J., Pradas-Arnal, F., & Gómez-López, L. I. (1998). The association between vasectomy and prostate cancer: a systematic review of the literature. Fertility and Sterility, 70(2), pp. 191-200.
Bernal-Delgado E, et al. The Association Between Vasectomy and Prostate Cancer: a Systematic Review of the Literature. Fertil Steril. 1998;70(2):191-200. PubMed PMID: 9696205.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The association between vasectomy and prostate cancer: a systematic review of the literature. AU - Bernal-Delgado,E, AU - Latour-Pérez,J, AU - Pradas-Arnal,F, AU - Gómez-López,L I, PY - 1998/8/8/pubmed PY - 1998/8/8/medline PY - 1998/8/8/entrez KW - Biology KW - Cancer KW - Diseases KW - Family Planning KW - Genitalia KW - Genitalia, Male KW - Literature Review KW - Male Sterilization KW - Neoplasms KW - Physiology KW - Prostate KW - Research Methodology KW - Risk Factors KW - Sterilization, Sexual KW - Urogenital System KW - Vasectomy SP - 191 EP - 200 JF - Fertility and sterility JO - Fertil. Steril. VL - 70 IS - 2 N2 - OBJECTIVE: To evaluate the possible association between vasectomy and prostate cancer. DESIGN: Systematic review of the literature. PATIENT(S): Fourteen original studies published between January 1985 and December 1996 that addressed the association between vasectomy and prostate cancer. MAIN OUTCOME MEASURE(S): The strength of the association was estimated with the use of a meta-analysis (DerSimonian and Laird method). A sensitivity analysis was conducted to assess the impact of different sources of heterogeneity. RESULT(S): Fourteen original papers were reviewed (5 cohort and 9 case-control studies). Relative risks ranged between 0.44 (95% confidence interval [CI] = 0.1-4.0) and 6.70 (95% CI = 2.1-21.6). The overall relative risk (DerSimonian and Laird estimate) was 1.23 (95% CI = 1.01-1.49). The sensitivity analysis showed that this measure was very sensitive to the study base, the type of design used, and the possibility of bias. Further, the funnel plot demonstrated the probable existence of publication bias. CONCLUSION(S): No causal association was found between vasectomy and prostate cancer. Individuals who have undergone vasectomy are not at high risk for the development of prostate cancer. SN - 0015-0282 UR - https://www.unboundmedicine.com/medline/citation/9696205/The_association_between_vasectomy_and_prostate_cancer:_a_systematic_review_of_the_literature_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015028298001423 DB - PRIME DP - Unbound Medicine ER -