Tags

Type your tag names separated by a space and hit enter

Determination of illicit and/or abused drugs and compounds of forensic interest in biosamples by capillary electrophoretic/electrokinetic methods.
J Chromatogr B Biomed Sci Appl. 1998 Aug 21; 713(1):27-49.JC

Abstract

The application of capillary electrophoresis (CE) methods in forensic toxicology for the determination of illicit and/or misused drugs in biological samples is reviewed in the present paper. Sample pretreatments and direct injection modes used in CE for analysis of drugs in biological fluids are briefly described. Besides, applications of separation methods based on capillary zone electrophoresis or micellar electrokinetic chromatography with UV absorbance detection to (i) analysis of drugs of abuse, (ii) analysis of other drugs and toxicants of potential forensic interest and (iii) for metabolism studies are reviewed. Also, alternative CE methods are briefly discussed, including capillary isotachophoresis and separation on mixed polymer networks. High sensitivity detection methods used for forensic drug analysis in biological samples are then presented, particularly those based on laser induced fluorescence. A glimpse of the first examples of application of CE-mass spectrometry in forensic toxicology is finally given.

Authors+Show Affiliations

Institute of Forensic Medicine, University of Verona, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9700551

Citation

Tagliaro, F, et al. "Determination of Illicit And/or Abused Drugs and Compounds of Forensic Interest in Biosamples By Capillary Electrophoretic/electrokinetic Methods." Journal of Chromatography. B, Biomedical Sciences and Applications, vol. 713, no. 1, 1998, pp. 27-49.
Tagliaro F, Turrina S, Pisi P, et al. Determination of illicit and/or abused drugs and compounds of forensic interest in biosamples by capillary electrophoretic/electrokinetic methods. J Chromatogr B Biomed Sci Appl. 1998;713(1):27-49.
Tagliaro, F., Turrina, S., Pisi, P., Smith, F. P., & Marigo, M. (1998). Determination of illicit and/or abused drugs and compounds of forensic interest in biosamples by capillary electrophoretic/electrokinetic methods. Journal of Chromatography. B, Biomedical Sciences and Applications, 713(1), 27-49.
Tagliaro F, et al. Determination of Illicit And/or Abused Drugs and Compounds of Forensic Interest in Biosamples By Capillary Electrophoretic/electrokinetic Methods. J Chromatogr B Biomed Sci Appl. 1998 Aug 21;713(1):27-49. PubMed PMID: 9700551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Determination of illicit and/or abused drugs and compounds of forensic interest in biosamples by capillary electrophoretic/electrokinetic methods. AU - Tagliaro,F, AU - Turrina,S, AU - Pisi,P, AU - Smith,F P, AU - Marigo,M, PY - 1998/8/13/pubmed PY - 1998/8/13/medline PY - 1998/8/13/entrez SP - 27 EP - 49 JF - Journal of chromatography. B, Biomedical sciences and applications JO - J. Chromatogr. B Biomed. Sci. Appl. VL - 713 IS - 1 N2 - The application of capillary electrophoresis (CE) methods in forensic toxicology for the determination of illicit and/or misused drugs in biological samples is reviewed in the present paper. Sample pretreatments and direct injection modes used in CE for analysis of drugs in biological fluids are briefly described. Besides, applications of separation methods based on capillary zone electrophoresis or micellar electrokinetic chromatography with UV absorbance detection to (i) analysis of drugs of abuse, (ii) analysis of other drugs and toxicants of potential forensic interest and (iii) for metabolism studies are reviewed. Also, alternative CE methods are briefly discussed, including capillary isotachophoresis and separation on mixed polymer networks. High sensitivity detection methods used for forensic drug analysis in biological samples are then presented, particularly those based on laser induced fluorescence. A glimpse of the first examples of application of CE-mass spectrometry in forensic toxicology is finally given. SN - 1387-2273 UR - https://www.unboundmedicine.com/medline/citation/9700551/Determination_of_illicit_and/or_abused_drugs_and_compounds_of_forensic_interest_in_biosamples_by_capillary_electrophoretic/electrokinetic_methods_ L2 - https://medlineplus.gov/medicines.html DB - PRIME DP - Unbound Medicine ER -