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The prevalence of gestational diabetes in a Sri Lankan antenatal clinic.
Ceylon Med J. 1998 Jun; 43(2):88-91.CM

Abstract

INTRODUCTION

Early diagnosis of gestational diabetes mellitus (GDM) is a prerequisite to reducing fetal and neonatal complications of GDM.

OBJECTIVES

(a) To ascertain the prevalence of GDM in a Sri Lankan pregnant population. Using the 75 g oral glucose tolerance test (GTT) and WHO criteria. (b) To establish the predictive value of a 50 g glucose challenge test (GCT) compared to the GTT (c) To compare the outcome of pregnancy in GDM with 'non-diabetic pregnancy' (NDP) STUDY DESIGN: Prospective study on a cohort of pregnant women attending antenatal clinics.

SETTING

Sri Jayawardenepura General Hospital (SJGH) RESULTS: Of the 721 patients, 131 (18%) had a positive GCT. 40 (5.5%) patients had GDM. If a one-hour GCT of 7.8 mmol/l was considered suspicious of GDM the sensitivity of the glucose challenge test was 63% and the specificity 84%. Statistically significant differences in the prevalence was found when the women were > 35 years [Relative risk (RR) = 3.87 (95% CI-2.06 to 7.27)] or the body mass index > or = 25. (RR = 2.45 (95 CI-1.30 to 4.61) Presence or absence of high parity, family history of diabetes or recurrent abortions had no significant impact on the prevalence of GDM. Mean birth weight was higher (p < 0.05) in GDM (3615 SD 103) than in NDP (2898 SD 143.6). The likelihood of having a caesarean section was higher (p < 0.01, Relative risk (RR) 2.50, 95% CI 1.56-3.95) in GDM when compared to NDP. A higher incidence of hydramnios (p < 0.01 RR 3.41 95% CI 1.44-8.05) was recorded in GDM when compared to NDP.

CONCLUSION

The prevalence of GDM in the antenatal clinics at SJGH is 5.5%. Traditional risk factors did not predict GDM. GDM is associated with a higher risk of caesarean section, hydramnios and macrosomia. Hence screening for GDM should be performed in all pregnant women at 24 to 28 weeks of pregnancy using a GCT.

Authors+Show Affiliations

Faculty of Medicine, University of Colombo, Sri Lanka.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

9704548

Citation

Siribaddana, S H., et al. "The Prevalence of Gestational Diabetes in a Sri Lankan Antenatal Clinic." The Ceylon Medical Journal, vol. 43, no. 2, 1998, pp. 88-91.
Siribaddana SH, Deshabandu R, Rajapakse D, et al. The prevalence of gestational diabetes in a Sri Lankan antenatal clinic. Ceylon Med J. 1998;43(2):88-91.
Siribaddana, S. H., Deshabandu, R., Rajapakse, D., Silva, K., & Fernando, D. J. (1998). The prevalence of gestational diabetes in a Sri Lankan antenatal clinic. The Ceylon Medical Journal, 43(2), 88-91.
Siribaddana SH, et al. The Prevalence of Gestational Diabetes in a Sri Lankan Antenatal Clinic. Ceylon Med J. 1998;43(2):88-91. PubMed PMID: 9704548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The prevalence of gestational diabetes in a Sri Lankan antenatal clinic. AU - Siribaddana,S H, AU - Deshabandu,R, AU - Rajapakse,D, AU - Silva,K, AU - Fernando,D J, PY - 1998/8/15/pubmed PY - 1998/8/15/medline PY - 1998/8/15/entrez KW - Asia KW - Cohort Analysis KW - Demographic Factors KW - Developing Countries KW - Diabetes Mellitus KW - Diseases KW - Examinations And Diagnoses KW - Fertility KW - Fertility Measurements KW - Fetus KW - Gestational Age KW - Glucose Tolerance Test KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Measurement KW - Population KW - Population Characteristics KW - Population Dynamics KW - Pregnancy KW - Pregnancy History KW - Pregnancy Outcomes KW - Pregnant Women KW - Prevalence KW - Prospective Studies KW - Reproduction KW - Research Methodology KW - Research Report KW - Southern Asia KW - Sri Lanka KW - Studies SP - 88 EP - 91 JF - The Ceylon medical journal JO - Ceylon Med J VL - 43 IS - 2 N2 - INTRODUCTION: Early diagnosis of gestational diabetes mellitus (GDM) is a prerequisite to reducing fetal and neonatal complications of GDM. OBJECTIVES: (a) To ascertain the prevalence of GDM in a Sri Lankan pregnant population. Using the 75 g oral glucose tolerance test (GTT) and WHO criteria. (b) To establish the predictive value of a 50 g glucose challenge test (GCT) compared to the GTT (c) To compare the outcome of pregnancy in GDM with 'non-diabetic pregnancy' (NDP) STUDY DESIGN: Prospective study on a cohort of pregnant women attending antenatal clinics. SETTING: Sri Jayawardenepura General Hospital (SJGH) RESULTS: Of the 721 patients, 131 (18%) had a positive GCT. 40 (5.5%) patients had GDM. If a one-hour GCT of 7.8 mmol/l was considered suspicious of GDM the sensitivity of the glucose challenge test was 63% and the specificity 84%. Statistically significant differences in the prevalence was found when the women were > 35 years [Relative risk (RR) = 3.87 (95% CI-2.06 to 7.27)] or the body mass index > or = 25. (RR = 2.45 (95 CI-1.30 to 4.61) Presence or absence of high parity, family history of diabetes or recurrent abortions had no significant impact on the prevalence of GDM. Mean birth weight was higher (p < 0.05) in GDM (3615 SD 103) than in NDP (2898 SD 143.6). The likelihood of having a caesarean section was higher (p < 0.01, Relative risk (RR) 2.50, 95% CI 1.56-3.95) in GDM when compared to NDP. A higher incidence of hydramnios (p < 0.01 RR 3.41 95% CI 1.44-8.05) was recorded in GDM when compared to NDP. CONCLUSION: The prevalence of GDM in the antenatal clinics at SJGH is 5.5%. Traditional risk factors did not predict GDM. GDM is associated with a higher risk of caesarean section, hydramnios and macrosomia. Hence screening for GDM should be performed in all pregnant women at 24 to 28 weeks of pregnancy using a GCT. SN - 0009-0875 UR - https://www.unboundmedicine.com/medline/citation/9704548/The_prevalence_of_gestational_diabetes_in_a_Sri_Lankan_antenatal_clinic_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -