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Influence of vitamin E acetate on stratum corneum hydration.
Arzneimittelforschung. 1998 Jul; 48(7):772-5.A

Abstract

The influence of vitamin E (tocopherol, CAS 10191-41-0) on stratum corneum hydration was tested in O/W and W/O emulsions. Additionally, the O/W emulsion was used in an in vivo/in vitro method to gravimetrically obtain evidence concerning the water-binding capacity of the stratum corneum. In the W/O emulsion, 2.5%, 5%, and 7.5% vitamin E were compared. With both types of emulsions, vitamin E increased the stratum corneum hydration statistically significantly (p = 0.0002). In addition, we could provide evidence of an enhanced water-binding capacity after treatment with vitamin E (p = 0.05). For the hydrating effect of vitamin E. its concentration is of importance. The optimum concentration turned out to be 5%.

Authors+Show Affiliations

Dermatological Clinic, Karlsruhe Municipal Hospital Complex, Germany.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

9706379

Citation

Gehring, W, et al. "Influence of Vitamin E Acetate On Stratum Corneum Hydration." Arzneimittel-Forschung, vol. 48, no. 7, 1998, pp. 772-5.
Gehring W, Fluhr J, Gloor M. Influence of vitamin E acetate on stratum corneum hydration. Arzneimittelforschung. 1998;48(7):772-5.
Gehring, W., Fluhr, J., & Gloor, M. (1998). Influence of vitamin E acetate on stratum corneum hydration. Arzneimittel-Forschung, 48(7), 772-5.
Gehring W, Fluhr J, Gloor M. Influence of Vitamin E Acetate On Stratum Corneum Hydration. Arzneimittelforschung. 1998;48(7):772-5. PubMed PMID: 9706379.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of vitamin E acetate on stratum corneum hydration. AU - Gehring,W, AU - Fluhr,J, AU - Gloor,M, PY - 1998/8/26/pubmed PY - 1998/8/26/medline PY - 1998/8/26/entrez SP - 772 EP - 5 JF - Arzneimittel-Forschung JO - Arzneimittelforschung VL - 48 IS - 7 N2 - The influence of vitamin E (tocopherol, CAS 10191-41-0) on stratum corneum hydration was tested in O/W and W/O emulsions. Additionally, the O/W emulsion was used in an in vivo/in vitro method to gravimetrically obtain evidence concerning the water-binding capacity of the stratum corneum. In the W/O emulsion, 2.5%, 5%, and 7.5% vitamin E were compared. With both types of emulsions, vitamin E increased the stratum corneum hydration statistically significantly (p = 0.0002). In addition, we could provide evidence of an enhanced water-binding capacity after treatment with vitamin E (p = 0.05). For the hydrating effect of vitamin E. its concentration is of importance. The optimum concentration turned out to be 5%. SN - 0004-4172 UR - https://www.unboundmedicine.com/medline/citation/9706379/Influence_of_vitamin_E_acetate_on_stratum_corneum_hydration_ L2 - https://medlineplus.gov/vitamine.html DB - PRIME DP - Unbound Medicine ER -