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Supplementation of general anaesthesia with tramadol or fentanyl in parturients undergoing elective caesarean section.
Can J Anaesth. 1998 Jul; 45(7):631-4.CJ

Abstract

PURPOSE

Tramadol has been recommended for analgesia in parturients undergoing vaginal delivery. The present report investigated the effect of tramadol versus fentanyl on umbilical vein (UV) blood gases and Apgar scores of neonates delivered via elective Caesarean section under general anaesthesia.

METHODS

Forty ASA I or II parturients undergoing elective Caesarean section were included in a randomized double-blinded study. The patients were divided into a tramadol (n = 20) and fentanyl groups (n = 20). During preoxygenation, one group received 100 mg tramadol i.v., while the second received 100 micrograms fentanyl. Anaesthesia was induced in both groups by 3 mg.kg-1 thiopentone and 1.5 mg.kg-1 succinylcholine was given to facilitate tracheal intubation. Anaesthesia was maintained during the induction-delivery period with nitrous oxide 50% in oxygen.

RESULTS

The umbilical vein PO2 was higher in the fentanyl (34 +/- 5 mmHg) than in the tramadol group (24 +/- 6 mmHg) (P < 0.01), while the UV PCO2 was higher in the tramadol group (50 +/- 5 vs 45 +/- 4 mmHg) (P < 0.01). The Apgar scores at one and five minutes were not different between the two groups. Post operatively, two patients in the tramadol group recalled the crying of their newborn at delivery.

CONCLUSION

Tramadol is associated with a high incidence of intraoperative maternal recall and can result in lower umbilical vein PO2 and higher PCO2 than in the fentanyl group.

Authors+Show Affiliations

Department of Anesthesiology, American University of Beirut, Beirut-Lebanon. abaraka@aub.edu.lbNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

9717593

Citation

Baraka, A, et al. "Supplementation of General Anaesthesia With Tramadol or Fentanyl in Parturients Undergoing Elective Caesarean Section." Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie, vol. 45, no. 7, 1998, pp. 631-4.
Baraka A, Siddik S, Assaf B. Supplementation of general anaesthesia with tramadol or fentanyl in parturients undergoing elective caesarean section. Can J Anaesth. 1998;45(7):631-4.
Baraka, A., Siddik, S., & Assaf, B. (1998). Supplementation of general anaesthesia with tramadol or fentanyl in parturients undergoing elective caesarean section. Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie, 45(7), 631-4.
Baraka A, Siddik S, Assaf B. Supplementation of General Anaesthesia With Tramadol or Fentanyl in Parturients Undergoing Elective Caesarean Section. Can J Anaesth. 1998;45(7):631-4. PubMed PMID: 9717593.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Supplementation of general anaesthesia with tramadol or fentanyl in parturients undergoing elective caesarean section. AU - Baraka,A, AU - Siddik,S, AU - Assaf,B, PY - 1998/8/26/pubmed PY - 1998/8/26/medline PY - 1998/8/26/entrez SP - 631 EP - 4 JF - Canadian journal of anaesthesia = Journal canadien d'anesthesie JO - Can J Anaesth VL - 45 IS - 7 N2 - PURPOSE: Tramadol has been recommended for analgesia in parturients undergoing vaginal delivery. The present report investigated the effect of tramadol versus fentanyl on umbilical vein (UV) blood gases and Apgar scores of neonates delivered via elective Caesarean section under general anaesthesia. METHODS: Forty ASA I or II parturients undergoing elective Caesarean section were included in a randomized double-blinded study. The patients were divided into a tramadol (n = 20) and fentanyl groups (n = 20). During preoxygenation, one group received 100 mg tramadol i.v., while the second received 100 micrograms fentanyl. Anaesthesia was induced in both groups by 3 mg.kg-1 thiopentone and 1.5 mg.kg-1 succinylcholine was given to facilitate tracheal intubation. Anaesthesia was maintained during the induction-delivery period with nitrous oxide 50% in oxygen. RESULTS: The umbilical vein PO2 was higher in the fentanyl (34 +/- 5 mmHg) than in the tramadol group (24 +/- 6 mmHg) (P < 0.01), while the UV PCO2 was higher in the tramadol group (50 +/- 5 vs 45 +/- 4 mmHg) (P < 0.01). The Apgar scores at one and five minutes were not different between the two groups. Post operatively, two patients in the tramadol group recalled the crying of their newborn at delivery. CONCLUSION: Tramadol is associated with a high incidence of intraoperative maternal recall and can result in lower umbilical vein PO2 and higher PCO2 than in the fentanyl group. SN - 0832-610X UR - https://www.unboundmedicine.com/medline/citation/9717593/Supplementation_of_general_anaesthesia_with_tramadol_or_fentanyl_in_parturients_undergoing_elective_caesarean_section_ L2 - https://doi.org/10.1007/BF03012091 DB - PRIME DP - Unbound Medicine ER -