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Effects of dietary coconut oil, butter and safflower oil on plasma lipids, lipoproteins and lathosterol levels.
Eur J Clin Nutr 1998; 52(9):650-4EJ

Abstract

OBJECTIVE

The aim of this present study was to determine plasma levels of lathosterol, lipids, lipoproteins and apolipoproteins during diets rich in butter, coconut fat and safflower oil.

DESIGN

The study consisted of sequential six week periods of diets rich in butter, coconut fat then safflower oil and measurements were made at baseline and at week 4 in each diet period.

SUBJECTS

Forty-one healthy Pacific island polynesians living in New Zealand participated in the trial.

INTERVENTIONS

Subjects were supplied with some foods rich in the test fats and were given detailed dietary advice which was reinforced regularly.

RESULTS

Plasma lathosterol concentration (P < 0.001), the ratio plasma lathosterol/cholesterol (P=0.04), low density lipoprotein (LDL) cholesterol (P<0.001) and apoB (P<0.001) levels were significantly different among the diets and were significantly lower during coconut and safflower oil diets compared with butter diets. Plasma total cholesterol, HDL cholesterol and apoA-levels were also significantly (P< or =0.001) different among the diets and were not significantly different between buffer and coconut diets.

CONCLUSIONS

These data suggest that cholesterol synthesis is lower during diets rich in coconut fat and safflower oil compared with diets rich in butter and might be associated with lower production rates of apoB-containing lipoproteins.

Authors+Show Affiliations

Department of Human Nutrition, University of Otago, Dunedin, New Zealand.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9756121

Citation

Cox, C, et al. "Effects of Dietary Coconut Oil, Butter and Safflower Oil On Plasma Lipids, Lipoproteins and Lathosterol Levels." European Journal of Clinical Nutrition, vol. 52, no. 9, 1998, pp. 650-4.
Cox C, Sutherland W, Mann J, et al. Effects of dietary coconut oil, butter and safflower oil on plasma lipids, lipoproteins and lathosterol levels. Eur J Clin Nutr. 1998;52(9):650-4.
Cox, C., Sutherland, W., Mann, J., de Jong, S., Chisholm, A., & Skeaff, M. (1998). Effects of dietary coconut oil, butter and safflower oil on plasma lipids, lipoproteins and lathosterol levels. European Journal of Clinical Nutrition, 52(9), pp. 650-4.
Cox C, et al. Effects of Dietary Coconut Oil, Butter and Safflower Oil On Plasma Lipids, Lipoproteins and Lathosterol Levels. Eur J Clin Nutr. 1998;52(9):650-4. PubMed PMID: 9756121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of dietary coconut oil, butter and safflower oil on plasma lipids, lipoproteins and lathosterol levels. AU - Cox,C, AU - Sutherland,W, AU - Mann,J, AU - de Jong,S, AU - Chisholm,A, AU - Skeaff,M, PY - 1998/10/2/pubmed PY - 1998/10/2/medline PY - 1998/10/2/entrez SP - 650 EP - 4 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 52 IS - 9 N2 - OBJECTIVE: The aim of this present study was to determine plasma levels of lathosterol, lipids, lipoproteins and apolipoproteins during diets rich in butter, coconut fat and safflower oil. DESIGN: The study consisted of sequential six week periods of diets rich in butter, coconut fat then safflower oil and measurements were made at baseline and at week 4 in each diet period. SUBJECTS: Forty-one healthy Pacific island polynesians living in New Zealand participated in the trial. INTERVENTIONS: Subjects were supplied with some foods rich in the test fats and were given detailed dietary advice which was reinforced regularly. RESULTS: Plasma lathosterol concentration (P < 0.001), the ratio plasma lathosterol/cholesterol (P=0.04), low density lipoprotein (LDL) cholesterol (P<0.001) and apoB (P<0.001) levels were significantly different among the diets and were significantly lower during coconut and safflower oil diets compared with butter diets. Plasma total cholesterol, HDL cholesterol and apoA-levels were also significantly (P< or =0.001) different among the diets and were not significantly different between buffer and coconut diets. CONCLUSIONS: These data suggest that cholesterol synthesis is lower during diets rich in coconut fat and safflower oil compared with diets rich in butter and might be associated with lower production rates of apoB-containing lipoproteins. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/9756121/Effects_of_dietary_coconut_oil_butter_and_safflower_oil_on_plasma_lipids_lipoproteins_and_lathosterol_levels_ L2 - https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html DB - PRIME DP - Unbound Medicine ER -