Tags

Type your tag names separated by a space and hit enter

[Continuous intrathecal infusion of baclofen. A new therapeutic method for spasticity].
Tidsskr Nor Laegeforen. 1998 Sep 10; 118(21):3256-60.TN

Abstract

Intrathecal administration of baclofen is now generally accepted as a powerful treatment of spasticity caused by spinal lesions. 35 patients with severe spasticity, 29 of spinal origin and six of supraspinal origin resistant to conservative treatment, had a programmable pump (Synchromed, Medtronic) for continuous intrathecal baclofen infusion implanted. The patients were followed-up for an average of 29 months (0-68). The initial effect of the treatment was positive for all patients; spasms were less frequent, there was remission of pain caused by cramps, and in some cases improved ambulation. In five patients, however, the pump was later removed: in two patients the pump ceased to be effective, two patients became infected, and one experienced multiple catheter problems. Problems with the catheter was the most common complication experienced, and this was seen in nine patients. Three patients died of the underlying disease. The majority of patients became accommodated to intrathecal baclofen and it was necessary to administer increasingly larger doses to maintain the clinical effect. Long-term control of spinal spasticity by intrathecal baclofen can be achieved in most patients, but close follow-up is necessary for assessing efficacy and refilling the pump.

Authors+Show Affiliations

Nevrokirurgisk avdeling Ullevål sykehus, Oslo.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

nor

PubMed ID

9772811

Citation

Berg-Johnsen, J, et al. "[Continuous Intrathecal Infusion of Baclofen. a New Therapeutic Method for Spasticity]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 118, no. 21, 1998, pp. 3256-60.
Berg-Johnsen J, Røste GK, Solgaard T, et al. [Continuous intrathecal infusion of baclofen. A new therapeutic method for spasticity]. Tidsskr Nor Laegeforen. 1998;118(21):3256-60.
Berg-Johnsen, J., Røste, G. K., Solgaard, T., & Lundar, T. (1998). [Continuous intrathecal infusion of baclofen. A new therapeutic method for spasticity]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 118(21), 3256-60.
Berg-Johnsen J, et al. [Continuous Intrathecal Infusion of Baclofen. a New Therapeutic Method for Spasticity]. Tidsskr Nor Laegeforen. 1998 Sep 10;118(21):3256-60. PubMed PMID: 9772811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Continuous intrathecal infusion of baclofen. A new therapeutic method for spasticity]. AU - Berg-Johnsen,J, AU - Røste,G K, AU - Solgaard,T, AU - Lundar,T, PY - 1998/10/17/pubmed PY - 1998/10/17/medline PY - 1998/10/17/entrez SP - 3256 EP - 60 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr. Nor. Laegeforen. VL - 118 IS - 21 N2 - Intrathecal administration of baclofen is now generally accepted as a powerful treatment of spasticity caused by spinal lesions. 35 patients with severe spasticity, 29 of spinal origin and six of supraspinal origin resistant to conservative treatment, had a programmable pump (Synchromed, Medtronic) for continuous intrathecal baclofen infusion implanted. The patients were followed-up for an average of 29 months (0-68). The initial effect of the treatment was positive for all patients; spasms were less frequent, there was remission of pain caused by cramps, and in some cases improved ambulation. In five patients, however, the pump was later removed: in two patients the pump ceased to be effective, two patients became infected, and one experienced multiple catheter problems. Problems with the catheter was the most common complication experienced, and this was seen in nine patients. Three patients died of the underlying disease. The majority of patients became accommodated to intrathecal baclofen and it was necessary to administer increasingly larger doses to maintain the clinical effect. Long-term control of spinal spasticity by intrathecal baclofen can be achieved in most patients, but close follow-up is necessary for assessing efficacy and refilling the pump. SN - 0029-2001 UR - https://www.unboundmedicine.com/medline/citation/9772811/[Continuous_intrathecal_infusion_of_baclofen__A_new_therapeutic_method_for_spasticity]_ L2 - http://www.diseaseinfosearch.org/result/6711 DB - PRIME DP - Unbound Medicine ER -