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Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease.
J Clin Pathol. 1976 Jul; 29(7):587-91.JC

Abstract

Jejunal lamina propria plasma cells and eosinophils and intraepithelial lymphocytes were raised in coeliac children on gluten-containing diets, but only intraepithelial lymphocytes were increased in patients on gluten-free diets. In contrast, lamina propria lymphocytes were reduced in children with coeliad disease on gluten-containing diets but were normal in paitents on gluten-free diets. In children with coeliac disease who were studied serially, lamina propria plasma cells and eosinophils and intraepithelial lymphocytes increased, and lamina propria lymphocytes decreased, within three months of the reintroduction of gluten to the diet. These observations are essentially similar to those made in the adult form of the disease and suggest that more than one type of immunological reaction is involved in the pathogenesis of the jejunal lesion.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

977769

Citation

Lancaster-Smith, M, et al. "Cellular Infiltrate of the Jejunum After Re-introduction of Dietary Gluten in Children With Treated Coeliac Disease." Journal of Clinical Pathology, vol. 29, no. 7, 1976, pp. 587-91.
Lancaster-Smith M, Packer S, Kumar PJ, et al. Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease. J Clin Pathol. 1976;29(7):587-91.
Lancaster-Smith, M., Packer, S., Kumar, P. J., & Harries, J. T. (1976). Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease. Journal of Clinical Pathology, 29(7), 587-91.
Lancaster-Smith M, et al. Cellular Infiltrate of the Jejunum After Re-introduction of Dietary Gluten in Children With Treated Coeliac Disease. J Clin Pathol. 1976;29(7):587-91. PubMed PMID: 977769.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease. AU - Lancaster-Smith,M, AU - Packer,S, AU - Kumar,P J, AU - Harries,J T, PY - 1976/7/1/pubmed PY - 1976/7/1/medline PY - 1976/7/1/entrez SP - 587 EP - 91 JF - Journal of clinical pathology JO - J Clin Pathol VL - 29 IS - 7 N2 - Jejunal lamina propria plasma cells and eosinophils and intraepithelial lymphocytes were raised in coeliac children on gluten-containing diets, but only intraepithelial lymphocytes were increased in patients on gluten-free diets. In contrast, lamina propria lymphocytes were reduced in children with coeliad disease on gluten-containing diets but were normal in paitents on gluten-free diets. In children with coeliac disease who were studied serially, lamina propria plasma cells and eosinophils and intraepithelial lymphocytes increased, and lamina propria lymphocytes decreased, within three months of the reintroduction of gluten to the diet. These observations are essentially similar to those made in the adult form of the disease and suggest that more than one type of immunological reaction is involved in the pathogenesis of the jejunal lesion. SN - 0021-9746 UR - https://www.unboundmedicine.com/medline/citation/977769/Cellular_infiltrate_of_the_jejunum_after_re_introduction_of_dietary_gluten_in_children_with_treated_coeliac_disease_ L2 - https://jcp.bmj.com/lookup/pmidlookup?view=long&pmid=977769 DB - PRIME DP - Unbound Medicine ER -