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Defecatory disorders in de novo Parkinsonians--colonic transit and electromyogram of the external anal sphincter.
Wien Klin Wochenschr. 1998 Aug 21; 110(15):535-7.WK

Abstract

Constipation is very common in Parkinson's disease. It is still not known whether constipation is due to a slow transit of the colon or an outlet obstruction. We examined 25 patients (11 women, 14 men, mean age 62 years) with newly diagnosed idiopathic Parkinson's disease. All patients had typical clinical symptoms (with an average score of 11.4 points on the Webster scale); the diagnosis was confirmed by 18F-Dopa-PET. In all patients the colon transit time was measured with radioopaque markers. Pudendal nerve lesions were excluded by neurography of the pudendal nerve. Electromyography of the external anal sphincter was performed with concentric needle electrodes in the right and left lateral position. Colon transit time in the patients averaged 3.7 days, with pathologically prolonged transit (> 4 days) in 6 patients (24%). Four patients (16%) showed mild neurogenic changes on sphincter EMG (16%). In three other cases (12%) long duration and large amplitude of motor unit action potentials (MUAPs), and a reduced interference pattern during maximal voluntary effort indicated a severe neurogenic lesion. One patient presented with involuntary contractions of the external anal sphincter at rest, which increased during strain (anism).

Authors+Show Affiliations

Fachbereich Neurologie und Klinische Neurophysiologie, Deutsche Klinik für Diagnostik, Wiesbaden, Federal Republic of Germany.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9782572

Citation

Jost, W H., and B Schrank. "Defecatory Disorders in De Novo Parkinsonians--colonic Transit and Electromyogram of the External Anal Sphincter." Wiener Klinische Wochenschrift, vol. 110, no. 15, 1998, pp. 535-7.
Jost WH, Schrank B. Defecatory disorders in de novo Parkinsonians--colonic transit and electromyogram of the external anal sphincter. Wien Klin Wochenschr. 1998;110(15):535-7.
Jost, W. H., & Schrank, B. (1998). Defecatory disorders in de novo Parkinsonians--colonic transit and electromyogram of the external anal sphincter. Wiener Klinische Wochenschrift, 110(15), 535-7.
Jost WH, Schrank B. Defecatory Disorders in De Novo Parkinsonians--colonic Transit and Electromyogram of the External Anal Sphincter. Wien Klin Wochenschr. 1998 Aug 21;110(15):535-7. PubMed PMID: 9782572.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Defecatory disorders in de novo Parkinsonians--colonic transit and electromyogram of the external anal sphincter. AU - Jost,W H, AU - Schrank,B, PY - 1998/10/23/pubmed PY - 1998/10/23/medline PY - 1998/10/23/entrez SP - 535 EP - 7 JF - Wiener klinische Wochenschrift JO - Wien. Klin. Wochenschr. VL - 110 IS - 15 N2 - Constipation is very common in Parkinson's disease. It is still not known whether constipation is due to a slow transit of the colon or an outlet obstruction. We examined 25 patients (11 women, 14 men, mean age 62 years) with newly diagnosed idiopathic Parkinson's disease. All patients had typical clinical symptoms (with an average score of 11.4 points on the Webster scale); the diagnosis was confirmed by 18F-Dopa-PET. In all patients the colon transit time was measured with radioopaque markers. Pudendal nerve lesions were excluded by neurography of the pudendal nerve. Electromyography of the external anal sphincter was performed with concentric needle electrodes in the right and left lateral position. Colon transit time in the patients averaged 3.7 days, with pathologically prolonged transit (> 4 days) in 6 patients (24%). Four patients (16%) showed mild neurogenic changes on sphincter EMG (16%). In three other cases (12%) long duration and large amplitude of motor unit action potentials (MUAPs), and a reduced interference pattern during maximal voluntary effort indicated a severe neurogenic lesion. One patient presented with involuntary contractions of the external anal sphincter at rest, which increased during strain (anism). SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/9782572/Defecatory_disorders_in_de_novo_Parkinsonians__colonic_transit_and_electromyogram_of_the_external_anal_sphincter_ L2 - https://medlineplus.gov/constipation.html DB - PRIME DP - Unbound Medicine ER -