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Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer.
CLAO J. 1998 Oct; 24(4):239-41.CJ

Abstract

PURPOSE

We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer.

METHODS

A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem.

RESULTS

Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment.

CONCLUSIONS

Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases.

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Authors+Show Affiliations

Lin A
Department of Ophthalmology, University of Florida College of Medicine, Gainesville 32610-0284, USA.
Driebe WT
No affiliation info available
Polack P
No affiliation info available

MeSH

Administration, TopicalAlcaligenesAnti-Bacterial AgentsBacterial InfectionsClavulanic AcidsContact LensesCorneaDrug Therapy, CombinationGasesHumansKeratitisKeratoplasty, PenetratingMaleMiddle AgedPermeabilityPostoperative ComplicationsTicarcillinTrimethoprim, Sulfamethoxazole Drug Combination

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

9800065

Citation

Lin, A, et al. "Alcaligenes Xylosoxidans Keratitis Post Penetrating Keratoplasty in a Rigid Gas Permeable Lens Wearer." The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc, vol. 24, no. 4, 1998, pp. 239-41.
Lin A, Driebe WT, Polack P. Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer. CLAO J. 1998;24(4):239-41.
Lin, A., Driebe, W. T., & Polack, P. (1998). Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer. The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc, 24(4), 239-41.
Lin A, Driebe WT, Polack P. Alcaligenes Xylosoxidans Keratitis Post Penetrating Keratoplasty in a Rigid Gas Permeable Lens Wearer. CLAO J. 1998;24(4):239-41. PubMed PMID: 9800065.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer. AU - Lin,A, AU - Driebe,W T,Jr AU - Polack,P, PY - 1998/11/4/pubmed PY - 2001/3/28/medline PY - 1998/11/4/entrez SP - 239 EP - 41 JF - The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc JO - CLAO J VL - 24 IS - 4 N2 - PURPOSE: We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer. METHODS: A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem. RESULTS: Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment. CONCLUSIONS: Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases. SN - 0733-8902 UR - https://www.unboundmedicine.com/medline/citation/9800065/Alcaligenes_xylosoxidans_keratitis_post_penetrating_keratoplasty_in_a_rigid_gas_permeable_lens_wearer_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=9800065.ui DB - PRIME DP - Unbound Medicine ER -