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Prevalence of venous reflux in the general population on duplex scanning: the Edinburgh vein study.

Abstract

PURPOSE

The prevalence of reflux in the deep and superficial venous systems in the Edinburgh population and the relationship between patterns of reflux and the presence of venous disease on clinical examination were studied.

METHODS

A cross-sectional survey was done on men and women ranging in age from 18 to 64 years, randomly selected from 12 general practices. The presence of varicose veins and chronic venous insufficiency was noted on clinical examination, as was the duration of venous reflux by means of duplex scanning in 8 vein segments on each leg. Results were compared using cut-off points for reflux duration (RD) of 0.5 seconds or more (RD >/= 0.5) and more than 1.0 second (RD > 1.0) to define reflux.

RESULTS

There were 1566 study participants, 867 women and 699 men. The prevalence of reflux was similar in the right and left legs. The proportion of participants with reflux was highest in the lower thigh long saphenous vein (LSV) segment (18.6% in the right leg and 17.5% in the left leg for RD >/= 0.5), followed by the above knee popliteal segments (12.3% in the right leg and 11.0% in the left leg for RD >/= 0.5), the below knee popliteal (11.3% in the right leg and 9.5% in the left leg for RD >/= 0.5), upper LSV (10.0% in the right leg and 10.8% in the left leg for RD >/= 0.5) segments, the common femoral vein segments (7.8% in the right leg and 8.0% in the left leg for RD >/= 0.5), the lower superficial femoral vein (SFV) segments (6.6% in the right leg and 6.4% in the left leg for RD >/= 0.5), and the upper SFV (5.2% in the right leg and 4.7% in the left leg for RD >/= 0.5) and short saphenous vein (SSV) (4.6% in the right leg and 5.6% in the left leg for an RD >/= 0.5) segments. In the superficial vein segments, there was little difference in the occurrence of reflux whether RD >/= 0.5 or RD > 1.0 was used; but in the different deep vein segments, the prevalence of reflux was 2 to 4 times greater for RD >/= 0.5 rather than RD > 1.0. Men had a higher prevalence of reflux in the deep vein segments than women, reaching statistical significance (P </=.01) in 4 of 5 segments for RD >/= 0.5. In general, the prevalence of reflux increased with age. Those with "venous disease" had a significantly higher prevalence of reflux in all vein segments than those with "no disease" (P </=.001).

CONCLUSION

The prevalence of venous reflux in the general population was related to the presence of "venous disease," although it was also present in those without clinically apparent disease. There was a higher prevalence of reflux in the deep veins in men than the deep veins in women. Follow-up study of the population will determine the extent to which reflux is a predictor of future disease and complications.

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  • Authors+Show Affiliations

    ,

    Wolfson Unit for Prevention of Peripheral Vascular Diseases, Department of Public Health Sciences, University of Edinburgh, and the Department of Medical Radiology, and the Department of Surgery, Royal Infirmary of Edinburgh, United Kingdom.

    , , , ,

    Source

    Journal of vascular surgery 28:5 1998 Nov pg 767-76

    MeSH

    Adolescent
    Adult
    Cross-Sectional Studies
    Female
    Humans
    Male
    Middle Aged
    Regional Blood Flow
    Scotland
    Ultrasonography, Doppler, Duplex
    Varicose Veins
    Venous Insufficiency

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    9808843

    Citation

    Evans, C J., et al. "Prevalence of Venous Reflux in the General Population On Duplex Scanning: the Edinburgh Vein Study." Journal of Vascular Surgery, vol. 28, no. 5, 1998, pp. 767-76.
    Evans CJ, Allan PL, Lee AJ, et al. Prevalence of venous reflux in the general population on duplex scanning: the Edinburgh vein study. J Vasc Surg. 1998;28(5):767-76.
    Evans, C. J., Allan, P. L., Lee, A. J., Bradbury, A. W., Ruckley, C. V., & Fowkes, F. G. (1998). Prevalence of venous reflux in the general population on duplex scanning: the Edinburgh vein study. Journal of Vascular Surgery, 28(5), pp. 767-76.
    Evans CJ, et al. Prevalence of Venous Reflux in the General Population On Duplex Scanning: the Edinburgh Vein Study. J Vasc Surg. 1998;28(5):767-76. PubMed PMID: 9808843.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prevalence of venous reflux in the general population on duplex scanning: the Edinburgh vein study. AU - Evans,C J, AU - Allan,P L, AU - Lee,A J, AU - Bradbury,A W, AU - Ruckley,C V, AU - Fowkes,F G, PY - 1998/11/11/pubmed PY - 1998/11/11/medline PY - 1998/11/11/entrez SP - 767 EP - 76 JF - Journal of vascular surgery JO - J. Vasc. Surg. VL - 28 IS - 5 N2 - PURPOSE: The prevalence of reflux in the deep and superficial venous systems in the Edinburgh population and the relationship between patterns of reflux and the presence of venous disease on clinical examination were studied. METHODS: A cross-sectional survey was done on men and women ranging in age from 18 to 64 years, randomly selected from 12 general practices. The presence of varicose veins and chronic venous insufficiency was noted on clinical examination, as was the duration of venous reflux by means of duplex scanning in 8 vein segments on each leg. Results were compared using cut-off points for reflux duration (RD) of 0.5 seconds or more (RD >/= 0.5) and more than 1.0 second (RD > 1.0) to define reflux. RESULTS: There were 1566 study participants, 867 women and 699 men. The prevalence of reflux was similar in the right and left legs. The proportion of participants with reflux was highest in the lower thigh long saphenous vein (LSV) segment (18.6% in the right leg and 17.5% in the left leg for RD >/= 0.5), followed by the above knee popliteal segments (12.3% in the right leg and 11.0% in the left leg for RD >/= 0.5), the below knee popliteal (11.3% in the right leg and 9.5% in the left leg for RD >/= 0.5), upper LSV (10.0% in the right leg and 10.8% in the left leg for RD >/= 0.5) segments, the common femoral vein segments (7.8% in the right leg and 8.0% in the left leg for RD >/= 0.5), the lower superficial femoral vein (SFV) segments (6.6% in the right leg and 6.4% in the left leg for RD >/= 0.5), and the upper SFV (5.2% in the right leg and 4.7% in the left leg for RD >/= 0.5) and short saphenous vein (SSV) (4.6% in the right leg and 5.6% in the left leg for an RD >/= 0.5) segments. In the superficial vein segments, there was little difference in the occurrence of reflux whether RD >/= 0.5 or RD > 1.0 was used; but in the different deep vein segments, the prevalence of reflux was 2 to 4 times greater for RD >/= 0.5 rather than RD > 1.0. Men had a higher prevalence of reflux in the deep vein segments than women, reaching statistical significance (P </=.01) in 4 of 5 segments for RD >/= 0.5. In general, the prevalence of reflux increased with age. Those with "venous disease" had a significantly higher prevalence of reflux in all vein segments than those with "no disease" (P </=.001). CONCLUSION: The prevalence of venous reflux in the general population was related to the presence of "venous disease," although it was also present in those without clinically apparent disease. There was a higher prevalence of reflux in the deep veins in men than the deep veins in women. Follow-up study of the population will determine the extent to which reflux is a predictor of future disease and complications. SN - 0741-5214 UR - https://www.unboundmedicine.com/medline/citation/9808843/Prevalence_of_venous_reflux_in_the_general_population_on_duplex_scanning:_the_Edinburgh_vein_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0741521498003383 DB - PRIME DP - Unbound Medicine ER -