[TSH receptor antibodies in the recurrent goiter after surgical treatment of Graves-Basedow disease].Pol Merkur Lekarski 1998; 4(23):257-8PM
The serious complication after surgical treatment is goitre renewai. Very important is therefore the correct diagnosis based also on laboratory investigation, enabling early detection of dysthyreosis. The aim of work was assessment of immunological states of thyroid gland of patients with goitre recurrence treated surgically because of Graves-Basedow, based on investigation of TSH receptor antibodies. The time from the surgery to the examination ranged from two to eleven years. The laboratory investigation contained determination of thyroxin, free thyroxin triiodothyronin, thyreotropin and antibodies directed against TSH receptor(TRAb). It has been found that average concentration of TRAb and frequency was significantly higher in recurrent goitre then in group without goitre renewal. The results of investigation indicates usefulness of determination of thyroid antibodies in diagnosis of recurrent goitre after surgical treatment of Graves-Basedow disease.