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Erythrocyte antioxidant activity and trace element levels in Behçet's disease.
Biol Trace Elem Res. 1998 Summer; 64(1-3):169-74.BT

Abstract

Selenium (Se), zinc (Zn), copper (Cu), and antioxidant enzyme (superoxide dismutase [SOD] and glutathione peroxidase [GSH-Px]) levels in sera were detected in Behçet patients. Age and sex matched controls were used to find out if oxidative stress takes place in the etiopathogenesis of Behçet's disease. Superoxide dismutase levels were found to be lower in the whole patients group when compared to controls. In whole patients and inactive patients' group Zn and Se levels were found to be higher, but not different in the active patients group when compared to controls. No significant difference was found between the groups as Cu and glutathione peroxidase levels were taken into consideration. According to the results of the present study, SOD level is low in Behçet's disease patients' sera independent from the phase of the disease, and as a result of decreased SOD activity, increased production of free oxygen radicals may play a role in the etiopathogenesis of the disease.

Authors+Show Affiliations

Tüzün A
GATA Dept. of Gastroenterology, Ankara, Turkey.
Aydin A
No affiliation info available
Turan M
No affiliation info available

MeSH

AntioxidantsBehcet SyndromeErythrocytesFemaleGlutathione PeroxidaseHumansMaleOxidative StressSeleniumSuperoxide DismutaseTrace ElementsZinc

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9845471

Citation

Tüzün, A, et al. "Erythrocyte Antioxidant Activity and Trace Element Levels in Behçet's Disease." Biological Trace Element Research, vol. 64, no. 1-3, 1998, pp. 169-74.
Tüzün A, Aydin A, Turan M. Erythrocyte antioxidant activity and trace element levels in Behçet's disease. Biol Trace Elem Res. 1998;64(1-3):169-74.
Tüzün, A., Aydin, A., & Turan, M. (1998). Erythrocyte antioxidant activity and trace element levels in Behçet's disease. Biological Trace Element Research, 64(1-3), 169-74.
Tüzün A, Aydin A, Turan M. Erythrocyte Antioxidant Activity and Trace Element Levels in Behçet's Disease. Biol Trace Elem Res. 1998;64(1-3):169-74. PubMed PMID: 9845471.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Erythrocyte antioxidant activity and trace element levels in Behçet's disease. AU - Tüzün,A, AU - Aydin,A, AU - Turan,M, PY - 1998/12/9/pubmed PY - 1998/12/9/medline PY - 1998/12/9/entrez SP - 169 EP - 74 JF - Biological trace element research JO - Biol Trace Elem Res VL - 64 IS - 1-3 N2 - Selenium (Se), zinc (Zn), copper (Cu), and antioxidant enzyme (superoxide dismutase [SOD] and glutathione peroxidase [GSH-Px]) levels in sera were detected in Behçet patients. Age and sex matched controls were used to find out if oxidative stress takes place in the etiopathogenesis of Behçet's disease. Superoxide dismutase levels were found to be lower in the whole patients group when compared to controls. In whole patients and inactive patients' group Zn and Se levels were found to be higher, but not different in the active patients group when compared to controls. No significant difference was found between the groups as Cu and glutathione peroxidase levels were taken into consideration. According to the results of the present study, SOD level is low in Behçet's disease patients' sera independent from the phase of the disease, and as a result of decreased SOD activity, increased production of free oxygen radicals may play a role in the etiopathogenesis of the disease. SN - 0163-4984 UR - https://www.unboundmedicine.com/medline/citation/9845471/Erythrocyte_antioxidant_activity_and_trace_element_levels_in_Beh��et's_disease_ L2 - https://dx.doi.org/10.1007/BF02783333 DB - PRIME DP - Unbound Medicine ER -