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[The significance of associated malformations of the central nervous system in myelomeningocele].
Tidsskr Nor Laegeforen. 1998 Nov 10; 118(27):4232-4.TN

Abstract

Neural tube defects are the most frequent congenital structural malformations in Norway. Approximately half of these are myelomeningocele. Infants with myelomeningocele frequently have hydrocephalus at birth. Problems with intracranial pressure may as well develop later. There are several reports on pathological corpus callosum and an increasing number of reports on cognitive problems in patients with myelomeningocele. Most patients with myelomeningocele have a tethered spinal cord, and some have syringomyelia. Chiari malformation type II is a malformation of the skull and brainstem which is frequently observed in individuals with myelomeningocele. Chiari malformation may cause severe respiratory problems in infants. Chiari malformation, tethered cord as well as syringomyelia are associated with a range of neurological problems which may progress in adulthood. Surgical intervention may improve the situation. Anaesthesia may induce neurological complications in individuals with Chiari malformation or syringomyelia. Since pregnancy and childbirth are associated with complications, women with myelomeningocele should be examined before they become pregnant. Children and adults with myelomeningocele should routinely undergo MRI examinations of caput and the spinal cord to clarify their anatomical situation.

Authors+Show Affiliations

Avdeling for medisinsk genetikk, Ullevål sykehus, Oslo.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

nor

PubMed ID

9857808

Citation

Christensen, B, and S Rand-Hendriksen. "[The Significance of Associated Malformations of the Central Nervous System in Myelomeningocele]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 118, no. 27, 1998, pp. 4232-4.
Christensen B, Rand-Hendriksen S. [The significance of associated malformations of the central nervous system in myelomeningocele]. Tidsskr Nor Laegeforen. 1998;118(27):4232-4.
Christensen, B., & Rand-Hendriksen, S. (1998). [The significance of associated malformations of the central nervous system in myelomeningocele]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 118(27), 4232-4.
Christensen B, Rand-Hendriksen S. [The Significance of Associated Malformations of the Central Nervous System in Myelomeningocele]. Tidsskr Nor Laegeforen. 1998 Nov 10;118(27):4232-4. PubMed PMID: 9857808.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The significance of associated malformations of the central nervous system in myelomeningocele]. AU - Christensen,B, AU - Rand-Hendriksen,S, PY - 1998/12/19/pubmed PY - 1998/12/19/medline PY - 1998/12/19/entrez SP - 4232 EP - 4 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 118 IS - 27 N2 - Neural tube defects are the most frequent congenital structural malformations in Norway. Approximately half of these are myelomeningocele. Infants with myelomeningocele frequently have hydrocephalus at birth. Problems with intracranial pressure may as well develop later. There are several reports on pathological corpus callosum and an increasing number of reports on cognitive problems in patients with myelomeningocele. Most patients with myelomeningocele have a tethered spinal cord, and some have syringomyelia. Chiari malformation type II is a malformation of the skull and brainstem which is frequently observed in individuals with myelomeningocele. Chiari malformation may cause severe respiratory problems in infants. Chiari malformation, tethered cord as well as syringomyelia are associated with a range of neurological problems which may progress in adulthood. Surgical intervention may improve the situation. Anaesthesia may induce neurological complications in individuals with Chiari malformation or syringomyelia. Since pregnancy and childbirth are associated with complications, women with myelomeningocele should be examined before they become pregnant. Children and adults with myelomeningocele should routinely undergo MRI examinations of caput and the spinal cord to clarify their anatomical situation. SN - 0029-2001 UR - https://www.unboundmedicine.com/medline/citation/9857808/[The_significance_of_associated_malformations_of_the_central_nervous_system_in_myelomeningocele]_ L2 - http://www.diseaseinfosearch.org/result/4602 DB - PRIME DP - Unbound Medicine ER -