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Senile dementia of the Binswanger's type.
Am Fam Physician. 1998 Dec; 58(9):2068-74.AF

Abstract

Senile dementia of the Binswanger's type is a term used to describe a dementia syndrome characterized by onset in the sixth or seventh decade of life, subcortical neurologic deficits, psychiatric disorders and evidence of hypertension or systemic vascular disease. The status of senile dementia of the Binswanger's type as a distinct entity is a matter of some controversy. The array of neuroimaging abnormalities and clinical findings attributed to this condition overlap with a number of other neuropathologies. Leukoaraiosis, or attenuation of subcortical white matter, seen on computed tomographic scans or magnetic resonance imaging of the brain, is a hallmark of senile dementia of the Binswanger's type. The clinical findings associated with Binswanger's disease are varied but typically include a progressive dementia, depression and "subcortical" dysfunction such as gait abnormalities, rigidity and neurogenic bladder. Treatment is largely supportive and includes a discussion about advanced directives, social support and antidepressant therapy. Control of hypertension and aspirin prophylaxis may help prevent further progression of white matter disease.

Authors+Show Affiliations

Department of Family Medicine, Wright State University School of Medicine, Dayton, Ohio, USA.No affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

9861880

Citation

Olsen, C G., and M E. Clasen. "Senile Dementia of the Binswanger's Type." American Family Physician, vol. 58, no. 9, 1998, pp. 2068-74.
Olsen CG, Clasen ME. Senile dementia of the Binswanger's type. Am Fam Physician. 1998;58(9):2068-74.
Olsen, C. G., & Clasen, M. E. (1998). Senile dementia of the Binswanger's type. American Family Physician, 58(9), 2068-74.
Olsen CG, Clasen ME. Senile Dementia of the Binswanger's Type. Am Fam Physician. 1998;58(9):2068-74. PubMed PMID: 9861880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Senile dementia of the Binswanger's type. AU - Olsen,C G, AU - Clasen,M E, PY - 1998/12/23/pubmed PY - 1998/12/23/medline PY - 1998/12/23/entrez SP - 2068 EP - 74 JF - American family physician JO - Am Fam Physician VL - 58 IS - 9 N2 - Senile dementia of the Binswanger's type is a term used to describe a dementia syndrome characterized by onset in the sixth or seventh decade of life, subcortical neurologic deficits, psychiatric disorders and evidence of hypertension or systemic vascular disease. The status of senile dementia of the Binswanger's type as a distinct entity is a matter of some controversy. The array of neuroimaging abnormalities and clinical findings attributed to this condition overlap with a number of other neuropathologies. Leukoaraiosis, or attenuation of subcortical white matter, seen on computed tomographic scans or magnetic resonance imaging of the brain, is a hallmark of senile dementia of the Binswanger's type. The clinical findings associated with Binswanger's disease are varied but typically include a progressive dementia, depression and "subcortical" dysfunction such as gait abnormalities, rigidity and neurogenic bladder. Treatment is largely supportive and includes a discussion about advanced directives, social support and antidepressant therapy. Control of hypertension and aspirin prophylaxis may help prevent further progression of white matter disease. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/9861880/Senile_dementia_of_the_Binswanger's_type_ L2 - https://www.aafp.org/link_out?pmid=9861880 DB - PRIME DP - Unbound Medicine ER -