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[Transdermal route as an alternative to oral administration of opioids in cancer pain].
Clin Ter. 1998 Jul-Aug; 149(4):277-80.CT

Abstract

Fentanyl TTS, the only transdermal opioid, represents a real tool for a better quality of life in patients with cancer pain. In this paper we report a short description of the pharmacologic properties and administration procedures of this drug that is a useful alternative when other opioids recommended on the third step of the WHO analgesic ladder, are ineffective or present unbearable side effects (nausea and/or vomiting-severe mucosites and dysphagia). In particular we indicated some changes and adjustments switching from morphine per os to fentanyl TTS. In addition we report the results of a study carried out in our Pain Therapy Center on 49 patients with severe oncologic pain, previously treated with opioids and other drugs associations. Our results indicated a good control of continuous nociceptive cancer pain, with a better quality of life and lesser side effects to respect the previous regime of orally opioids.

Authors+Show Affiliations

Burza M
Istituto Regina Elena, Servizio di Terapia del Dolore e Rianimazione, Roma, Italia.
Ginobbi P
No affiliation info available
Fusco G
No affiliation info available
Laurenzi L
No affiliation info available
Tirelli W
No affiliation info available
Arcuri E
No affiliation info available

MeSH

Administration, CutaneousAdministration, OralAnalgesics, OpioidFentanylHumansMorphineNeoplasmsPain, IntractablePalliative Care

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

9866889

Citation

Burza, M, et al. "[Transdermal Route as an Alternative to Oral Administration of Opioids in Cancer Pain]." La Clinica Terapeutica, vol. 149, no. 4, 1998, pp. 277-80.
Burza M, Ginobbi P, Fusco G, et al. [Transdermal route as an alternative to oral administration of opioids in cancer pain]. Clin Ter. 1998;149(4):277-80.
Burza, M., Ginobbi, P., Fusco, G., Laurenzi, L., Tirelli, W., & Arcuri, E. (1998). [Transdermal route as an alternative to oral administration of opioids in cancer pain]. La Clinica Terapeutica, 149(4), 277-80.
Burza M, et al. [Transdermal Route as an Alternative to Oral Administration of Opioids in Cancer Pain]. Clin Ter. 1998 Jul-Aug;149(4):277-80. PubMed PMID: 9866889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Transdermal route as an alternative to oral administration of opioids in cancer pain]. AU - Burza,M, AU - Ginobbi,P, AU - Fusco,G, AU - Laurenzi,L, AU - Tirelli,W, AU - Arcuri,E, PY - 1998/12/29/pubmed PY - 1998/12/29/medline PY - 1998/12/29/entrez SP - 277 EP - 80 JF - La Clinica terapeutica JO - Clin Ter VL - 149 IS - 4 N2 - Fentanyl TTS, the only transdermal opioid, represents a real tool for a better quality of life in patients with cancer pain. In this paper we report a short description of the pharmacologic properties and administration procedures of this drug that is a useful alternative when other opioids recommended on the third step of the WHO analgesic ladder, are ineffective or present unbearable side effects (nausea and/or vomiting-severe mucosites and dysphagia). In particular we indicated some changes and adjustments switching from morphine per os to fentanyl TTS. In addition we report the results of a study carried out in our Pain Therapy Center on 49 patients with severe oncologic pain, previously treated with opioids and other drugs associations. Our results indicated a good control of continuous nociceptive cancer pain, with a better quality of life and lesser side effects to respect the previous regime of orally opioids. SN - 0009-9074 UR - https://www.unboundmedicine.com/medline/citation/9866889/[Transdermal_route_as_an_alternative_to_oral_administration_of_opioids_in_cancer_pain]_ L2 - http://www.diseaseinfosearch.org/result/5395 DB - PRIME DP - Unbound Medicine ER -