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Effect of norepinephrine on ouabain-sensitive, K+-dependent p-nitrophenylphosphatase activity in strial marginal cells of the cochlea in normal and reserpinized guinea pigs.
Acta Otolaryngol. 1998 Nov; 118(6):817-20.AO

Abstract

On the basolateral infoldings of the strial marginal cells in the cochlea, Na K ATPase activity is abundant. To clarify the humoral control by norepinephrine, K-NPPase activity of strial marginal cells in the cochlea was investigated in normal, reserpine, norepinephrine (NE), reserpine plus NE-treated guinea pigs using a cerium-based method. K-NPPase activity was almost completely decreased 3-20 days after reserpine administration. At 10 days after reserpinization and following NE repeated treatment, enzyme activity was detectable. These results suggested that norepinephrine might restore and regulate strial K-NPPase activity.

Authors+Show Affiliations

Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Japan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9870626

Citation

Kanoh, N. "Effect of Norepinephrine On Ouabain-sensitive, K+-dependent P-nitrophenylphosphatase Activity in Strial Marginal Cells of the Cochlea in Normal and Reserpinized Guinea Pigs." Acta Oto-laryngologica, vol. 118, no. 6, 1998, pp. 817-20.
Kanoh N. Effect of norepinephrine on ouabain-sensitive, K+-dependent p-nitrophenylphosphatase activity in strial marginal cells of the cochlea in normal and reserpinized guinea pigs. Acta Otolaryngol. 1998;118(6):817-20.
Kanoh, N. (1998). Effect of norepinephrine on ouabain-sensitive, K+-dependent p-nitrophenylphosphatase activity in strial marginal cells of the cochlea in normal and reserpinized guinea pigs. Acta Oto-laryngologica, 118(6), 817-20.
Kanoh N. Effect of Norepinephrine On Ouabain-sensitive, K+-dependent P-nitrophenylphosphatase Activity in Strial Marginal Cells of the Cochlea in Normal and Reserpinized Guinea Pigs. Acta Otolaryngol. 1998;118(6):817-20. PubMed PMID: 9870626.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of norepinephrine on ouabain-sensitive, K+-dependent p-nitrophenylphosphatase activity in strial marginal cells of the cochlea in normal and reserpinized guinea pigs. A1 - Kanoh,N, PY - 1998/12/31/pubmed PY - 1998/12/31/medline PY - 1998/12/31/entrez SP - 817 EP - 20 JF - Acta oto-laryngologica JO - Acta Otolaryngol VL - 118 IS - 6 N2 - On the basolateral infoldings of the strial marginal cells in the cochlea, Na K ATPase activity is abundant. To clarify the humoral control by norepinephrine, K-NPPase activity of strial marginal cells in the cochlea was investigated in normal, reserpine, norepinephrine (NE), reserpine plus NE-treated guinea pigs using a cerium-based method. K-NPPase activity was almost completely decreased 3-20 days after reserpine administration. At 10 days after reserpinization and following NE repeated treatment, enzyme activity was detectable. These results suggested that norepinephrine might restore and regulate strial K-NPPase activity. SN - 0001-6489 UR - https://www.unboundmedicine.com/medline/citation/9870626/Effect_of_norepinephrine_on_ouabain_sensitive_K+_dependent_p_nitrophenylphosphatase_activity_in_strial_marginal_cells_of_the_cochlea_in_normal_and_reserpinized_guinea_pigs_ L2 - https://www.tandfonline.com/doi/full/10.1080/00016489850182503 DB - PRIME DP - Unbound Medicine ER -