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Concurrent administration of clozapine and ECT: a successful therapeutic strategy for a patient with treatment-resistant schizophrenia.
J ECT. 1998 Dec; 14(4):280-3.JE

Abstract

A male patient with a 4-year history of schizophrenic disorder, treated in the past with several conventional neuroleptics, atypical antipsychotics, as well as adjunctive therapies, was hospitalized because of treatment resistance/intolerance to pharmacotherapy. During 60 weeks of hospitalization, the patient was treated with conventional neuroleptics or clozapine monotherapy and with concurrent bilateral electroconvulsive therapy (ECT). The patient showed inadequate response to conventional neuroleptics or clozapine without ECT. Concurrent administration of pimozide and ECT resulted in a brief period of improvement. However, concurrent administration of clozapine and ECT resulted in substantial improvement. Our observation suggests that combination treatment with clozapine and ECT can be safe and effective.

Authors+Show Affiliations

Mental Health and Behavioral Science Department, Department of Veterans Affairs Medical Center, Omaha, NE 68105, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

9871852

Citation

Bhatia, S C., et al. "Concurrent Administration of Clozapine and ECT: a Successful Therapeutic Strategy for a Patient With Treatment-resistant Schizophrenia." The Journal of ECT, vol. 14, no. 4, 1998, pp. 280-3.
Bhatia SC, Bhatia SK, Gupta S. Concurrent administration of clozapine and ECT: a successful therapeutic strategy for a patient with treatment-resistant schizophrenia. J ECT. 1998;14(4):280-3.
Bhatia, S. C., Bhatia, S. K., & Gupta, S. (1998). Concurrent administration of clozapine and ECT: a successful therapeutic strategy for a patient with treatment-resistant schizophrenia. The Journal of ECT, 14(4), 280-3.
Bhatia SC, Bhatia SK, Gupta S. Concurrent Administration of Clozapine and ECT: a Successful Therapeutic Strategy for a Patient With Treatment-resistant Schizophrenia. J ECT. 1998;14(4):280-3. PubMed PMID: 9871852.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Concurrent administration of clozapine and ECT: a successful therapeutic strategy for a patient with treatment-resistant schizophrenia. AU - Bhatia,S C, AU - Bhatia,S K, AU - Gupta,S, PY - 1999/1/1/pubmed PY - 1999/1/1/medline PY - 1999/1/1/entrez SP - 280 EP - 3 JF - The journal of ECT JO - J ECT VL - 14 IS - 4 N2 - A male patient with a 4-year history of schizophrenic disorder, treated in the past with several conventional neuroleptics, atypical antipsychotics, as well as adjunctive therapies, was hospitalized because of treatment resistance/intolerance to pharmacotherapy. During 60 weeks of hospitalization, the patient was treated with conventional neuroleptics or clozapine monotherapy and with concurrent bilateral electroconvulsive therapy (ECT). The patient showed inadequate response to conventional neuroleptics or clozapine without ECT. Concurrent administration of pimozide and ECT resulted in a brief period of improvement. However, concurrent administration of clozapine and ECT resulted in substantial improvement. Our observation suggests that combination treatment with clozapine and ECT can be safe and effective. SN - 1095-0680 UR - https://www.unboundmedicine.com/medline/citation/9871852/Concurrent_administration_of_clozapine_and_ECT:_a_successful_therapeutic_strategy_for_a_patient_with_treatment_resistant_schizophrenia_ L2 - http://Insights.ovid.com/pubmed?pmid=9871852 DB - PRIME DP - Unbound Medicine ER -