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Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children.
J Med Virol. 1999 Feb; 57(2):193-7.JM

Abstract

In a prospective comparative study, the use of combined analysis of upper respiratory tract swab samples and cerebrospinal fluid (CSF) samples was assessed to improve the detection rate of enteroviral meningitis in children. An enterovirus was detected in 32% of patients with aseptic meningitis when testing CSF samples alone compared with 71.5% when combining CSF and respiratory tract findings. An enterovirus was detected in 17% of respiratory tract samples in an age- and sex-matched control group without meningitis. Thus, combining the examination of upper respiratory tract with CSF findings may improve the detection rate of enteroviral meningitis. Upper respiratory tract samples should be included in the diagnosis scheme to differentiate benign enteroviral meningitis from other life-threatening infections of the central nervous system.

Authors+Show Affiliations

Laboratoire de Virologie, Centre National de Référence des Entérovirus et de l'Hépatite A, Lyon, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

9892407

Citation

Foray, S, et al. "Evaluation of Combining Upper Respiratory Tract Swab Samples With Cerebrospinal Fluid Examination for the Diagnosis of Enteroviral Meningitis in Children." Journal of Medical Virology, vol. 57, no. 2, 1999, pp. 193-7.
Foray S, Pailloud F, Thouvenot D, et al. Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children. J Med Virol. 1999;57(2):193-7.
Foray, S., Pailloud, F., Thouvenot, D., Floret, D., Aymard, M., & Lina, B. (1999). Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children. Journal of Medical Virology, 57(2), 193-7.
Foray S, et al. Evaluation of Combining Upper Respiratory Tract Swab Samples With Cerebrospinal Fluid Examination for the Diagnosis of Enteroviral Meningitis in Children. J Med Virol. 1999;57(2):193-7. PubMed PMID: 9892407.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children. AU - Foray,S, AU - Pailloud,F, AU - Thouvenot,D, AU - Floret,D, AU - Aymard,M, AU - Lina,B, PY - 1999/1/19/pubmed PY - 2000/6/20/medline PY - 1999/1/19/entrez SP - 193 EP - 7 JF - Journal of medical virology JO - J Med Virol VL - 57 IS - 2 N2 - In a prospective comparative study, the use of combined analysis of upper respiratory tract swab samples and cerebrospinal fluid (CSF) samples was assessed to improve the detection rate of enteroviral meningitis in children. An enterovirus was detected in 32% of patients with aseptic meningitis when testing CSF samples alone compared with 71.5% when combining CSF and respiratory tract findings. An enterovirus was detected in 17% of respiratory tract samples in an age- and sex-matched control group without meningitis. Thus, combining the examination of upper respiratory tract with CSF findings may improve the detection rate of enteroviral meningitis. Upper respiratory tract samples should be included in the diagnosis scheme to differentiate benign enteroviral meningitis from other life-threatening infections of the central nervous system. SN - 0146-6615 UR - https://www.unboundmedicine.com/medline/citation/9892407/Evaluation_of_combining_upper_respiratory_tract_swab_samples_with_cerebrospinal_fluid_examination_for_the_diagnosis_of_enteroviral_meningitis_in_children_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0146-6615&date=1999&volume=57&issue=2&spage=193 DB - PRIME DP - Unbound Medicine ER -