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[Food and food additives hypersensitivity in adult asthmatics. III. Adverse reaction to sulfites in adult asthmatics].
Arerugi 1998; 47(11):1163-7A

Abstract

OBJECTS

Many studies show that sulfites cause multiple atopic manifestations by oral challenge in USA and Europe, however, there are few reports of sulfites sensitivity in Japan. The aim of this study establishes the presence of sulfites hypersensitivities in asthmatic subjects in Japan.

SUBJECTS AND METHOD

Twenty adult asthmatic patients, who were non-steroid-dependent and without a suggestive history of sulfite sensitivity, underwent challenge with oral solution of metabisulfite.

RESULT

Of 12 patients reacted to metabisulfite. They demonstrated airway obstruction 5 (41.7%), urticaria 4 (36.7%), skin manifestation 2 (16.7%) and nasal congestion 1 (8.3%). All patients who demonstrated airway obstruction, were sensitive to aspirin.

CONCLUSION

Oral sulfite challenge should be made in patients with urticaria, that are not able to find out causative antigen, even though no suggestive history of sulfite sensitivity.

Authors+Show Affiliations

Department of Allergy and Respiratory Medicine, Doai Memorial Hospital.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

9893332

Citation

Arai, Y, et al. "[Food and Food Additives Hypersensitivity in Adult Asthmatics. III. Adverse Reaction to Sulfites in Adult Asthmatics]." Arerugi = [Allergy], vol. 47, no. 11, 1998, pp. 1163-7.
Arai Y, Muto H, Sano Y, et al. [Food and food additives hypersensitivity in adult asthmatics. III. Adverse reaction to sulfites in adult asthmatics]. Arerugi. 1998;47(11):1163-7.
Arai, Y., Muto, H., Sano, Y., & Ito, K. (1998). [Food and food additives hypersensitivity in adult asthmatics. III. Adverse reaction to sulfites in adult asthmatics]. Arerugi = [Allergy], 47(11), pp. 1163-7.
Arai Y, et al. [Food and Food Additives Hypersensitivity in Adult Asthmatics. III. Adverse Reaction to Sulfites in Adult Asthmatics]. Arerugi. 1998;47(11):1163-7. PubMed PMID: 9893332.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Food and food additives hypersensitivity in adult asthmatics. III. Adverse reaction to sulfites in adult asthmatics]. AU - Arai,Y, AU - Muto,H, AU - Sano,Y, AU - Ito,K, PY - 1999/1/20/pubmed PY - 1999/1/20/medline PY - 1999/1/20/entrez SP - 1163 EP - 7 JF - Arerugi = [Allergy] JO - Arerugi VL - 47 IS - 11 N2 - OBJECTS: Many studies show that sulfites cause multiple atopic manifestations by oral challenge in USA and Europe, however, there are few reports of sulfites sensitivity in Japan. The aim of this study establishes the presence of sulfites hypersensitivities in asthmatic subjects in Japan. SUBJECTS AND METHOD: Twenty adult asthmatic patients, who were non-steroid-dependent and without a suggestive history of sulfite sensitivity, underwent challenge with oral solution of metabisulfite. RESULT: Of 12 patients reacted to metabisulfite. They demonstrated airway obstruction 5 (41.7%), urticaria 4 (36.7%), skin manifestation 2 (16.7%) and nasal congestion 1 (8.3%). All patients who demonstrated airway obstruction, were sensitive to aspirin. CONCLUSION: Oral sulfite challenge should be made in patients with urticaria, that are not able to find out causative antigen, even though no suggestive history of sulfite sensitivity. SN - 0021-4884 UR - https://www.unboundmedicine.com/medline/citation/9893332/[Food_and_food_additives_hypersensitivity_in_adult_asthmatics__III__Adverse_reaction_to_sulfites_in_adult_asthmatics]_ L2 - https://medlineplus.gov/foodallergy.html DB - PRIME DP - Unbound Medicine ER -