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New developments in understanding the etiology of Parkinson's disease and in its treatment.
Curr Opin Neurobiol. 1998 Dec; 8(6):783-90.CO

Abstract

Important recent advances have been made in understanding the etiology and pathogenesis of Parkinson's disease, as well as in developing novel treatments. Two newly identified genes, alpha-synuclein and parkin, have been linked to parkinsonism. In addition, disturbances to the normal basal ganglia circuits in Parkinson's patients are being described at both anatomical and physiological levels. These developments provide a strong scientific basis for novel medical and surgical strategies to treat the profound motor disturbances in patients with Parkinson's disease.

Authors+Show Affiliations

Department of Surgery, University of Toronto, The Toronto Hospital, Western Division, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada. lozano@playfair.utoronto.caNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

9914234

Citation

Lozano, A M., et al. "New Developments in Understanding the Etiology of Parkinson's Disease and in Its Treatment." Current Opinion in Neurobiology, vol. 8, no. 6, 1998, pp. 783-90.
Lozano AM, Lang AE, Hutchison WD, et al. New developments in understanding the etiology of Parkinson's disease and in its treatment. Curr Opin Neurobiol. 1998;8(6):783-90.
Lozano, A. M., Lang, A. E., Hutchison, W. D., & Dostrovsky, J. O. (1998). New developments in understanding the etiology of Parkinson's disease and in its treatment. Current Opinion in Neurobiology, 8(6), 783-90.
Lozano AM, et al. New Developments in Understanding the Etiology of Parkinson's Disease and in Its Treatment. Curr Opin Neurobiol. 1998;8(6):783-90. PubMed PMID: 9914234.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New developments in understanding the etiology of Parkinson's disease and in its treatment. AU - Lozano,A M, AU - Lang,A E, AU - Hutchison,W D, AU - Dostrovsky,J O, PY - 1999/1/23/pubmed PY - 1999/1/23/medline PY - 1999/1/23/entrez SP - 783 EP - 90 JF - Current opinion in neurobiology JO - Curr Opin Neurobiol VL - 8 IS - 6 N2 - Important recent advances have been made in understanding the etiology and pathogenesis of Parkinson's disease, as well as in developing novel treatments. Two newly identified genes, alpha-synuclein and parkin, have been linked to parkinsonism. In addition, disturbances to the normal basal ganglia circuits in Parkinson's patients are being described at both anatomical and physiological levels. These developments provide a strong scientific basis for novel medical and surgical strategies to treat the profound motor disturbances in patients with Parkinson's disease. SN - 0959-4388 UR - https://www.unboundmedicine.com/medline/citation/9914234/New_developments_in_understanding_the_etiology_of_Parkinson's_disease_and_in_its_treatment_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0959-4388(98)80122-0 DB - PRIME DP - Unbound Medicine ER -