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Rhinoviruses: important respiratory pathogens.
Ann Med. 1998 Dec; 30(6):529-37.AM

Abstract

The most frequent viruses associated with respiratory infections are human rhinoviruses (HRVs). Although the majority of HRV infections are mild and self-limited, HRV is an important cause of respiratory disease across all age groups. Recent studies using reverse transcriptase polymerase chain reaction to detect HRV genomes have established the importance of HRVs in predisposing to or causing otitis media, sinusitis and exacerbations of asthma, as well as other lower respiratory tract disorders. Among elderly people, infants and immunocompromised hosts HRV infections are often associated with lower respiratory tract morbidity and rarely mortality. How often active viral replication occurs in the middle ear, sinuses or the lower respiratory tract remains to be determined. However, the high incidence of HRV infections and their frequent association with upper and lower respiratory tract complications highlight the need for more effective means of prevention and treatment.

Authors+Show Affiliations

Department of Otorhinolaryngology, Helsinki University Central Hospital, Finland. anne.pitkaranta@helsinki.fiNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

9920354

Citation

Pitkäranta, A, and F G. Hayden. "Rhinoviruses: Important Respiratory Pathogens." Annals of Medicine, vol. 30, no. 6, 1998, pp. 529-37.
Pitkäranta A, Hayden FG. Rhinoviruses: important respiratory pathogens. Ann Med. 1998;30(6):529-37.
Pitkäranta, A., & Hayden, F. G. (1998). Rhinoviruses: important respiratory pathogens. Annals of Medicine, 30(6), 529-37.
Pitkäranta A, Hayden FG. Rhinoviruses: Important Respiratory Pathogens. Ann Med. 1998;30(6):529-37. PubMed PMID: 9920354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rhinoviruses: important respiratory pathogens. AU - Pitkäranta,A, AU - Hayden,F G, PY - 1999/1/27/pubmed PY - 1999/1/27/medline PY - 1999/1/27/entrez SP - 529 EP - 37 JF - Annals of medicine JO - Ann Med VL - 30 IS - 6 N2 - The most frequent viruses associated with respiratory infections are human rhinoviruses (HRVs). Although the majority of HRV infections are mild and self-limited, HRV is an important cause of respiratory disease across all age groups. Recent studies using reverse transcriptase polymerase chain reaction to detect HRV genomes have established the importance of HRVs in predisposing to or causing otitis media, sinusitis and exacerbations of asthma, as well as other lower respiratory tract disorders. Among elderly people, infants and immunocompromised hosts HRV infections are often associated with lower respiratory tract morbidity and rarely mortality. How often active viral replication occurs in the middle ear, sinuses or the lower respiratory tract remains to be determined. However, the high incidence of HRV infections and their frequent association with upper and lower respiratory tract complications highlight the need for more effective means of prevention and treatment. SN - 0785-3890 UR - https://www.unboundmedicine.com/medline/citation/9920354/Rhinoviruses:_important_respiratory_pathogens_ L2 - https://www.tandfonline.com/doi/full/10.3109/07853899709002600 DB - PRIME DP - Unbound Medicine ER -